Thiophenol → HCID 20069003、化合物
反応式
[C:1]1([SH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(N(CC)CC)C.C(S([C:19]1[S:20][C:21]([C:26]#[N:27])=[CH:22][C:23]=1[C:24]#[N:25])=O)C>C(#N)C>[C:1]1([S:7][C:19]2[S:20][C:21]([C:26]#[N:27])=[CH:22][C:23]=2[C:24]#[N:25])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
5
実験手順
4.4 ml of thiophenol and 5.0 ml of triethylamine are added, while stirring, to a solution of 8.9 g of 2-ethylsulphinyl-3,5-dicyanothiophene, obtained according to Example I, in 100 ml of acetonitrile. After leaving to stand overnight, the reaction mixture is refluxed for 8 hours. After evaporating the solvent, the residue is taken up in methylene chloride and chromatographed over a 1 l dry silica gel column. The desired product is obtained in a yield of 9.07 g; melting-point 68°-71° C. Optionally, any 2-alkylsulphinyl compound may be used as the starting substance.