7-Methyl-oct-6-en-1-ol → Isononanol
反応式
[CH3:1][C:2]([CH3:10])=[CH:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9]>CO.[Pd]>[CH3:1][CH:2]([CH3:10])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][OH:9]参加物
4
実験手順
A solution of 7-methyl-oct-6-en-1-ol (1.42 g, 10.0 mmol) in MeOH (70 mL) was hydrogenated with Pd—C (0.40 g, 10% w/w) in a Parr apparatus at 50 psi of H2 overnight. The catalyst was removed by filtration, and the filtrate was evaporated under reduced pressure to give 7-methyl-octan-1-ol (1.38 g, 96%) as a colorless oil: 1H NMR (300 MHz, CDCl3) δ 3.64 (2H, t, J=6.6 Hz), 1.54 (3H, m), 1.10–1.44 (8H, m), 0.88 (3H, s), 0.85 (3H, s); 13C NMR (75 MHz, CDCl3) δ 63.28, 39.21, 33.06, 29.98, 28.24, 27.64, 26.06, 22.94.
後処理
- customThe catalyst was removed by filtration
- customthe filtrate was evaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-ed23eba753104b989acd5556d6c144e0
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07091357B2
反応ノート
読み込み中…