HCID 178420353、化合物 → HCID 178511580、化合物
反応式
C([N:8](CC1C=CC=CC=1)[C@H:9]1[CH2:14][CH2:13][C@H:12]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)[CH2:11][CH2:10]1)C1C=CC=CC=1>CO.[Pd]>[O:18]1[CH2:17][CH2:16][N:15]([C@H:12]2[CH2:11][CH2:10][C@H:9]([NH2:8])[CH2:14][CH2:13]2)[CH2:20][CH2:19]1参加物
4
実験手順
7.2 g (16.4 mmol) of trans-dibenzyl-4-morpholino-cyclohexylamine were dissolved in 100 mL of MeOH and hydrogenated on 1.4 g of Pd/C (10%) at 30-50° C. The solvent was eliminated in vacuo and the residue was crystallised from ethanol and conc. HCl. Yield: 3.9 g (93%); m.p. 312° C.
後処理
- customthe residue was crystallised from ethanol and conc. HCl
出典と根拠
- ORDレコード
- ord-57cec909f1144059938b0e1211713190
- 出典データセット
- uspto-grants-2005_03
- 特許番号
- US06861422B2
反応ノート
読み込み中…