Dimethylformamide → 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-[3-(4-methyl-1-piperazinyl)propyl]-2H-pyridazin-3-one

反応式

[CH:1]1([CH2:4][N:5]2[C:10](=[O:11])[C:9]([CH2:12][CH:13](C(OC(C)(C)C)=O)[C:14](OC(C)(C)C)=O)=[CH:8][C:7]([C:28]3[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([F:36])[CH:29]=3)=[N:6]2)[CH2:3][CH2:2]1.[H-].[Na+].C(OC(C)(C)C)(=O)CC(OC(C)(C)C)=O.BrC[C:56]1[C:57](=O)[N:58]([CH2:71][CH:72]2CC2)N=C(C2C=CC(OC)=C(F)C=2)C=1.[CH3:76][N:77](C)C=O>O>[CH:1]1([CH2:4][N:5]2[C:10](=[O:11])[C:9]([CH2:12][CH2:13][CH2:14][N:58]3[CH2:57][CH2:56][N:77]([CH3:76])[CH2:72][CH2:71]3)=[CH:8][C:7]([C:28]3[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[C:30]([F:36])[CH:29]=3)=[N:6]2)[CH2:3][CH2:2]1