Iodine → 6-(1-fluoroethyl)-5-iodo-4-pyrimidone
反応式
[F:1][CH:2]([C:4]1[N:9]=[CH:8][NH:7][C:6](=[O:10])[CH:5]=1)[CH3:3].[I:11]Cl.II.ClCl>C(O)(=O)C>[F:1][CH:2]([C:4]1[N:9]=[CH:8][NH:7][C:6](=[O:10])[C:5]=1[I:11])[CH3:3]参加物
6
実験手順
To an acetic acid (150 ml) solution of 6-(1fluoroethyl)-4-pyrimidone (56.8 g) was added dropwise under room temperature and stirring an acetic acid solution of iodine monochloride prepared by adding iodine (50.8 g) to acetic acid (500 ml) and blowing chlorine (15 g) thereinto under room temperature and stirring, and the resulting mixture was stirred for 6 hours.
後処理
- customprepared
- stirringthe resulting mixture was stirred for 6 hours
出典と根拠
- ORDレコード
- ord-4abd0c6191b643289218bc490ab01772
- 出典データセット
- uspto-grants-2005_03
- 特許番号
- US06867212B2
反応ノート
読み込み中…