3-Methoxyaniline → Tert-butyl 4-(3-methoxyanilino)piperidine-1-carboxylate

反応式

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[CH:18]=1>>[CH3:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH:23][CH:11]2[CH2:12][CH2:13][N:8]([C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:7])[CH2:9][CH2:10]2)[CH:18]=1

参加物

反応物 2

HCID 108243-Methoxyaniline

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

生成物 1

HCID 22557965Tert-butyl 4-(3-methoxyanilino)piperidine-1-carboxylate

実験手順

1-(tert-Butoxycarbonyl)-4-piperidone (4.78 g) and m-anisidine (2.96 g) were condensed in the same manner as described in Preparation Example 37 to give the title compound.

後処理

customcondensed in the same manner
customas described in Preparation Example 37

出典と根拠

ORDレコード: ord-f20dfa4df1d04aa795351d55cd3ddff7
出典データセット: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06867221B2

反応ノート

読み込み中…