Pteridine → Vinylpteridine

反応式

[N:1]1[C:10]2[C:5](=[N:6][CH:7]=[CH:8][N:9]=2)[CH:4]=[N:3][CH:2]=1.NC1N=C(N)[C:19]2[C:14](=NC=C(C=C)N=2)N=1.ClCC(=O)C=NO.NC1C=CC=CN=1>>[CH:14]([C:2]1[N:3]=[CH:4][C:5]2[C:10](=[N:9][CH:8]=[CH:7][N:6]=2)[N:1]=1)=[CH2:19]

参加物

反応物 4

HCID 1043Pteridine

HCID 104392-Aminopyridine

HCID 6815174Chloropyruvaldoxime

HCID 98129832,4-Diamino-6-vinylpteridine

生成物 1

HCID 22062458Vinylpteridine収率 15%

実験手順

An interesting extension of the above systems is the preparation and use of a pteridine-based monomer. Such an example is 2,4-diamino-6-vinylpteridine (XIII). This molecule is synthesised in five synthetic steps, from -chloropyruvaldoxime, in 15% yield following the method of Taylor & Kobayashi (J. Org. Chem., 38, 2187-2821 (1973)). 6. Aminopyridine Based Monomers

後処理

customThis molecule is synthesised in five synthetic steps

出典と根拠

ORDレコード: ord-fe1722fb04a04481b25ea7d43abfb8c8
出典データセット: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06870021B2

反応ノート

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