5-Methoxy-3-phenyl-3H-isobenzofuran-1-one → 2-Benzyl-4-methoxybenzoic acid
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[O:7][CH:6]2[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(O)C.[Pd]>[CH2:6]([C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:11]=[CH:10][C:9]=1[C:8]([OH:12])=[O:7])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1参加物
4
実験手順
To a solution of 9 (12.0 g, 50 mmol) in ethanol was added 10% palladium on carbon (1.5 g). The resulting suspension was hydrogenated at 60 psi for 18 h. Filtration through celite followed by removal of the solvent in vacuo gave 10 as a white solid (11.0 g, 45.5 mmol, 91.1%).
後処理
- filtrationFiltration through celite
- customfollowed by removal of the solvent in vacuo
出典と根拠
- ORDレコード
- ord-3f5122da7540414fbce02b3069b1e3fe
- 出典データセット
- uspto-grants-2005_03
- 特許番号
- US06870055B2
反応ノート
読み込み中…