3-(4-Benzyloxyphenyl)-2-methoxypropanoic acid methyl ester → Methyl 3-(4-hydroxyphenyl)-2-methoxypropanoate
反応式
[CH3:1][O:2][C:3](=[O:22])[CH:4]([O:20][CH3:21])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12]CC2C=CC=CC=2)=[CH:8][CH:7]=1>CO.[Pd]>[CH3:1][O:2][C:3](=[O:22])[CH:4]([O:20][CH3:21])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1参加物
4
実験手順
3-(4-Benzyloxyphenyl)-2-methoxypropanoic acid methyl ester (1.91 g; 6.36 mmole) was hydrogenated in methanol (30 ml) using Pd/C (5%, wet, 0.9 g) as catalyst. The mixture was filtered through celite and the filtrate was evaporated in vacuo to give 1.16 g (yield 87%) of 3-(4-hydroxyphenyl)-2-methoxypropanoic acid methyl ester.
後処理
- filtrationThe mixture was filtered through celite
- customthe filtrate was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-1c9d470edc554c7aa88194000e7fb9be
- 出典データセット
- uspto-grants-2003_10
- 特許番号
- US06630600B1
反応ノート
読み込み中…