3-(4-Benzyloxyphenyl)-2-ethoxy-3-methylacrylic acid ethyl ester → HCID 54190417、化合物
反応式
[CH2:1]([O:3][C:4](=[O:25])[C:5]([O:22][CH2:23][CH3:24])=[C:6]([C:8]1[CH:13]=[CH:12][C:11]([O:14]CC2C=CC=CC=2)=[CH:10][CH:9]=1)[CH3:7])[CH3:2]>C(OCC)(=O)C.[Pd]>[CH2:1]([O:3][C:4](=[O:25])[CH:5]([O:22][CH2:23][CH3:24])[CH:6]([C:8]1[CH:9]=[CH:10][C:11]([OH:14])=[CH:12][CH:13]=1)[CH3:7])[CH3:2]参加物
4
実験手順
3-(4-Benzyloxyphenyl)-2-ethoxy-3-methylacrylic acid ethyl ester (1.58 g; 4.64 mmole) was hydrogenated at atmospheric pressure in ethyl acetate (20 ml) using Pd/C (wet) as catalyst. After filtration through celite, the solvent was evaporated in vacuo to give (1.1 g; yield 94%) of 3-(4-hydroxyphenyl)-2-ethoxybutanoic acid ethyl ester as a diastereomeric mixture.
後処理
- filtrationAfter filtration through celite
- customthe solvent was evaporated in vacuo
出典と根拠
- ORDレコード
- ord-4d29bf98154a4b8bbfa5327c49dc6c1a
- 出典データセット
- uspto-grants-2003_10
- 特許番号
- US06630600B1
反応ノート
読み込み中…