3-(4-Benzyloxy-3-methoxyphenyl)-2-ethoxyacrylic acid ethyl ester → 3-(4-Benzyloxy-3-methoxyphenyl)-2-ethoxypropanoic acid ethyl ester

HRID 987293

反応式

[CH2:1]([O:3][C:4](=[O:26])[C:5]([O:23][CH2:24][CH3:25])=[CH:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[C:9]([O:21][CH3:22])[CH:8]=1)[CH3:2]>C(OCC)(=O)C.[Pd]>[CH2:1]([O:3][C:4](=[O:26])[CH:5]([O:23][CH2:24][CH3:25])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[C:9]([O:21][CH3:22])[CH:8]=1)[CH3:2]

参加物

実験手順

3-(4-Benzyloxy-3-methoxyphenyl)-2-ethoxyacrylic acid ethyl ester (5.5 g, 15.4 mmole) was dissolved in ethyl acetate and hydrogenated using Pd/C (dry, 5%). The reaction mixture was filtered through celite. Evaporation of the filtrate gave 4 g (97% yield) of 3-(4-benzyloxy-3-methoxyphenyl)-2-ethoxypropanoic acid ethyl ester.

後処理

filtrationThe reaction mixture was filtered through celite
customEvaporation of the filtrate

出典と根拠

ORDレコード: ord-643d5dcc0cdc4665afdff22b52cc4807
出典データセット: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06630600B1

反応式

参加物

反応物 1

生成物 1

試薬・触媒・溶媒 2

実験手順

後処理

出典と根拠

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