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HRID 990584作成日:2026年10月27日

Diethylene Glycol Monoethyl Ether → Amitriptyline ketamine

https://huagongshe.com/reaction/990584

反応式

関与物質

役割名称HCID仕込み量
反応物Diethylene Glycol Monoethyl EtherHCID 8146—
反応物Amitriptyline HydrochlorideHCID 11065—
反応物Ketamine HydrochlorideHCID 15851—
生成物Amitriptyline ketamineHCID 9892707—

反応手順

0.3750 gm ketamine hydrochloride USP and 0.750 gm amitriptyline hydrochloride USP are combined and wetted with 2.0 ml of ethoxy diglycol reagent, and stirred into 75 gm of the base cream prepared as per example 3 and triple milled. The cream-type mixture contains ketamine hydrochloride at 5 mg/ml and amitriptyline hydrochloride at 10 mg/ml.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06461600B1
出典データセットuspto-grants-2002_10
ORD IDord-e770c9deff2d4242b4c06fba70b039da
出典メモuspto-grants-2002_10