3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl ester → 3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid

HRID 993485ノート

反応式

HRID 993485 の反応式
C([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([O:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:17]=2[Cl:23])[CH:6]=1)C>C(O)C.[OH-].[Na+]>[Cl:23][C:17]1[CH:18]=[C:19]([Cl:22])[CH:20]=[CH:21][C:16]=1[CH2:15][CH2:14][O:13][C:7]1[CH:6]=[C:5]([CH:10]=[CH:9][C:8]=1[O:11][CH3:12])[C:4]([OH:24])=[O:3]

参加物

4

反応物 1

HCID 154803313-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl ester

生成物 1

HCID 154803323-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid収率 73%

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 14798Sodium Hydroxide溶媒

実験手順

A solution of 3.6 g (9.8 mmol) of 3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl ester in 30 ml of ethanol and 5.4 ml of 2N sodium hydroxide solution was stirred at room temperature for 12 h. The precipitate was filtered off. The resulting solid was stirred with 5 ml of 2N HCl and filtered to give 2.44 g (73%) of the title compound.

後処理

  1. filtrationThe precipitate was filtered off
  2. filtrationfiltered

出典と根拠

ORDレコード
ord-711d81b5cadd4bed9286c06dda74a7d1
出典データセット
uspto-grants-2002_10
特許番号
US06472562B1

反応ノート

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