N-히드록시프탈이미드

N-Hydroxyphthalimide

HCID 10665CAS 524-38-9
부분 구조 검색유사 구조 찾기

기본 정보

표준 SMILES
O=C1c2ccccc2C(=O)N1O
InChIKey
CFMZSMGAMPBRBE-UHFFFAOYSA-N
분자식
C8H5NO3
평균 분자량
163.13 g/mol
단동위원소 질량
163.02694302

개요

causes contact dermititis

이름 및 식별자

우선 이름
N-Hydroxyphthalimide
IUPAC
2-hydroxyisoindole-1,3-dione
현지명
N-히드록시프탈이미드
영어명
N-Hydroxyphthalimide
분자식
C8H5NO3
분자량
163.13

이름 및 동의어

N-HYDROXYPHTHALIMIDE524-38-92-Hydroxyphthalimide1H-Isoindole-1,3(2H)-dione, 2-hydroxy-Phthalimide, N-hydroxy-BXI99M81X0NSC-770F 802DTXSID7060170RefChem:830142DTXCID1041188208-358-1
이름 더 보기
N-히드록시프탈이미드nhpihydroxyphthalimideHOPHTN-Hydrophthalimide
2-hydroxyisoindoline-1,3-dione2-Hydroxy-1H-isoindole-1,3(2H)-dione2-hydroxyisoindole-1,3-dioneMFCD000058912-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione2-oxidanylisoindole-1,3-dioneCHEMBL2760572-hydroxy-isoindole-1,3-dione

데이터베이스 식별자

CAS
524-38-9
PubChem CID
10665
DTXSID
DTXSID7060170
ChEMBL
CHEMBL276057
UNII
BXI99M81X0
EC Number
208-358-1
Nikkaji
J26.847J

물성

구조 계산 물성

XLogP
0.8
극성 표면적
57.6 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
0
무거운 원자 수
12

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Other Nitrogen Rings
SpringerMaterials PropertiesNuclear quadrupole resonance spectroscopy
Physical DescriptionYellowish or colorless solid; [Merck Index] White or off-white crystalline powder; [Alfa Aesar MSDS]
Ionization Efficiency · 6건

Negative

-0.43

10.5

Agilent XCT

Electrospray ionization

ammonia (10nM)

물리화학적 성질

녹는점
233 °C · 233 °C (dec.) (lit.)
끓는 점
290.19 °C · 290.19°C (rough estimate)
밀도
1.64 g/cm3 · 1.64 g/cm3
증기압
0 Pa · 0Pa at 25℃
굴절률
1.551 · 1.5510 (estimate)
저장 조건
Keep in dark place,Sealed in dry,Room Temperature

화학적 성질

N-Hydroxyphthalimide is yellow moist powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 152 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 3건

Chemical: 1H-Isoindole-1,3(2H)-dione, 2-hydroxy-

Status: Cease Manufacture Update: 24-03-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/19261

1H-Isoindole-1,3(2H)-dione, 2-hydroxy-: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryIntravenous LD50 (mouse) = 178 mg/kg; [RTECS] Causes contact dermatitis. [ChemIDplus] A skin and strong eye irritant; [Alfa Aesar MSDS] See N-Aminophthalimide.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

독성 정보

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
TI5200000
HS 번호
29251995
risk_code
36/37/38
hazard_code
Xi

화학 및 산업

용도 및 제조

UsesUsed as a catalyst for oxidation reactions; [Merck Index]
General Manufacturing Information1H-Isoindole-1,3(2H)-dione, 2-hydroxy-: ACTIVE

응용 분야

용도N-Hydroxyphthalimide，additives in to DCC method of peptide synthesis used to improve yield of optically pure product.

상·하류 제품 정보

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

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