4,5-디아미노플루오레세인
4,5-Diaminofluorescein
기본 정보
- CAS
205391-01-1- 표준 SMILES
Nc1cc2c(cc1N)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21- InChIKey
LTYUPYUWXRTNFQ-UHFFFAOYSA-N- 분자식
- C20H14N2O5
- 평균 분자량
- 362.3 g/mol
- 단동위원소 질량
- 362.09027155
개요
4,5-Diaminofluorescein is an organic molecular entity. It is functionally related to a dibenzopyran.
이름 및 식별자
- 우선 이름
- 4,5-Diaminofluorescein
- IUPAC
- 5,6-diamino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
- 현지명
- 4,5-디아미노플루오레세인
- 영어명
- 4,5-Diaminofluorescein
- 분자식
- C20H14N2O5
- 분자량
- 362.34
이름 및 동의어
4,5-DiaminofluoresceinDTXSID60443252DAF-2 (chromophore)RefChem:96427DTXCID60394073205391-01-1DAF-25,6-Diamino-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one5,6-diamino-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-oneSpiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 5,6-diamino-3',6'-dihydroxy-MFCD05865100DAF 2
이름 더 보기
4,5-디아미노플루오레세인5-Diaminofluorescein5,6-DIAMINOFLUORESCEIN45-DIAMINOFLUORESCEIN4,5-Diaminofluorescein, DAF-2DAF-2, Fluorescent nitric oxide probe4,5-Diaminofluorescein-Isopropanol adduct (1:2)2-(3,6-DIHYDROXY-9H-XANTHEN-9-YL)-4,5-DIAMINO-BENZOIC ACID
DAF-2;DAF2;5,6-DiaminofluoresceinAS-78359DAF-2-CAS 205391-01-1-CalbiochemC20H14N2O5orb2567220SCHEMBL8383527SCHEMBL29363014CHEBI:229536
데이터베이스 식별자
- CAS
205391-01-1- PubChem CID
- 10666340
- DTXSID
DTXSID60443252- ChEBI
CHEBI:229536- Nikkaji
- J974.002C
물성
구조 계산 물성
- XLogP
- 2.1
- 극성 표면적
- 128 Ų
- 수소 결합 공여자 수
- 4
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 27
- 형식 전하
- 0
- 복잡도
- 589
물리화학적 성질
- 끓는 점
- 760.832 · 760.832±60.00 °C(Press: 760.00 Torr)(predicted)
- 밀도
- 1.696 · 1.696±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- 저장 조건
- 2 · 2-8°C
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 9.319 · 9.319±0.20(predicted)
- 색상
- Brown to black
- InChI
- 1S/C20H14N2O5/c21-15-7-11-14(8-16(15)22)20(27-19(11)25)12-3-1-9(23)5-17(12)26-18-6-10(24)2-4-13(18)20/h1-8,23-24H,21-22H2
- InChIKey
- LTYUPYUWXRTNFQ-UHFFFAOYSA-N
- SMILES
- Nc1cc2c(cc1N)C(=O)OC32c4c(cc(cc4)O)Oc5c3ccc(c5)O
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 3
- risk_code
- 22-36/37/38
- hazard_code
- Xn,Xi
- safety_code
- 23-26-36
- F 고인화성물질
- 8-10-23
- 스토리지 클래스
- 10 - Combustible liquids
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
응용 분야
개요DAF-2 is a sensitive fluorescent indicator commonly used for the detection of nitric oxide (NO). It reacts with NO in the presence of oxygen to yield the highly fluorescent triazolofluorescein (DAF-2T). Fluorescence is monitored using excitation and emission wavelengths of 485 and 538 nM, respectively. At neutral pH the detection limit for NO is 2-5 nM.
용도DAF-2 is highly sensitive reagent for NO detection and determination of nitric oxide synthase activity.
관련 반응
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