L-락타이드

Lactide, L-

HCID 107983CAS 33135-50-1

기본 정보

표준 SMILES: C[C@@H]1OC(=O)[C@H](C)OC1=O
InChIKey: JJTUDXZGHPGLLC-IMJSIDKUSA-N
분자식: C6H8O4
평균 분자량: 144.12 g/mol
단동위원소 질량: 144.04225874

개요

Lactide, L- is under investigation in clinical trial NCT05450471 (Effectiveness of Endonasal Polymeric Implant for Chronic Rhinosinusitis).

이름 및 식별자

우선 이름: Lactide, L-
IUPAC: (3S,6S)-3,6-dimethyl-1,4-dioxane-2,5-dione
현지명: L-락타이드
영어명: L-Lactide
분자식: C6H8O4
분자량: 144.13

이름 및 동의어

L-Lactide4511-42-6L-(-)-LactideL,L-DilactideLactide, L-(-)-L-DilactidePurasorb LLL-Lactide(3S-cis)-3,6-Dimethyl-1,4-dioxane-2,5-dioneUNII-IJ13TO4NO1IJ13TO4NO1EINECS 224-832-0

이름 더 보기

L-락타이드LACTIDEL-LAL-(-)-DILACTIDE(3S)-CIS-3,6-DIMETHYL-1,4-DIOXANE-2,5-DIONEactide-(-)-L(3S,6S)

EC 224-832-01,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S-cis)-P-DIOXANE-2,5-DIONE, 3,6-DIMETHYL-, L-1,4-DIOXANE-2,5-DIONE, 3,6-DIMETHYL-, (3S,5S)-RefChem:7658224-832-0(3S,6S)-3,6-dimethyl-1,4-dioxane-2,5-dioneL-Dilactide

데이터베이스 식별자

CAS: 33135-50-1、4511-42-6
PubChem CID: 107983
DTXSID: DTXSID5049655
UNII: IJ13TO4NO1
EC Number: 224-832-0
Nikkaji: J150.826A

물성

구조 계산 물성

XLogP: 0.6
극성 표면적: 52.6 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 4
회전 가능 결합 수: 0
무거운 원자 수: 10
형식 전하: 0
복잡도: 155

물리화학적 성질

녹는점: 92 · 92-94 °C(lit.)
끓는 점: 255 °C · 255°C
밀도: 1.186 · 1.186±0.06 g/cm3(Predicted)
증기압: 0.311 Pa · 0.311Pa at 25℃
굴절률: 1.4475 · 1.4475
저장 조건: 2 · 2-8°C
용해도: 클로로포름 및 메탄올에 용해됩니다. 벤젠에 약간 용해됩니다.
물리적 상태: 고체
색상: 흰색에서 황백색까지
수용성: 16.7 g/L · 16.7g/L at 20℃
BRN: 82124 · 82124
안정성: 흡습성
InChI: 1S/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3/t3-,4-/m0/s1
InChIKey: JJTUDXZGHPGLLC-IMJSIDKUSA-N
SMILES: C[C@@H]1OC(=O)[C@H](C)OC1=O
LogP: 0.4 at · 0.4 at 25℃
EPA: 1 · 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)- (4511-42-6)

화학적 성질

White crystal

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H314 (10.9%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P321, P337+P317, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 183 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 01-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/11212

Hazard Classes and CategoriesSkin Corr. 1B (10.9%)

안전 데이터

wgk: 3
tsca: TSCA listed
HS 번호: 29322090
risk_code: 36/37/38-36
hazard_code: Xi
safety_code: 26-37/39
Hazard Classifications: Eye Irrit. 2
스토리지 클래스: 13 - Non Combustible Solids

화학 및 산업

용도 및 제조

General Manufacturing Information1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3S,6S)-: ACTIVE

응용 분야

용도(3S)-cis-3,6-Dimethyl-1,4-dioxane-2,5-dione may be used in the synthesis of optically active terpyridine containing poly(L-lactide)s, polydisperse lactic acid oligomers, bicyclic and tricyclic lactide derivatives.