3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulfonate (HCID 122145)

이름 및 식별자

우선 이름: 3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulfonate
IUPAC: 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]-2-hydroxypropane-1-sulfonate
영어명: Chapso
분자식: C32H58N2O8S
분자량: 630.88

이름 및 동의어

chapso82473-24-33-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonateV9N9RGA14M3-((3-cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulfonate3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propane sulfonateRefChem:919931-PROPANAMINIUM, 2-HYDROXY-N,N-DIMETHYL-3-SULFO-N-(3-(((3ALPHA,5BETA,7ALPHA,12ALPHA)-3,7,12-TRIHYDROXY-24-OXOCHOLAN-24-YL)AMINO)PROPYL)-, INNER SALT617-338-5MFCD000810793-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]-2-hydroxypropane-1-sulfonate(2-hydroxy-3-sulfopropyl)-dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azanium

이름 더 보기

Hydroxy analogCHAPSO extrapureCHAPSO detergentCHAPSO SIGMAULTRACHAPSO,ELECTROPHORESISGRADECHAPSO 96% For BiochemistryCHAPSO Buffer extrapure, 99%CHAPSO ELECTROPHORESIS REAGENT

3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]-2-hydroxypropane-1-sulfonateUNII-V9N9RGA14MC32H58N2O8SCHAPSO, BioXtraSCHEMBL594591orb2308659orb2900242CHAPSO, >=98%

데이터베이스 식별자

CAS: 82473-24-3
PubChem CID: 122145
DTXSID: DTXSID901002705
UNII: V9N9RGA14M
EC Number: 617-338-5
Nikkaji: J725.177G

물성

구조 계산 물성

XLogP: 1.9
극성 표면적: 176 Å²
수소 결합 공여자 수: 5
수소 결합 수용자 수: 8
회전 가능 결합 수: 11
무거운 원자 수: 43
형식 전하: 0
복잡도: 1,070

물리화학적 성질

녹는점: 184 · 184-186 °C(lit.)
밀도: 1.0453 · 1.0453 (rough estimate)
굴절률: 1.69 · 1.6900 (estimate)
저장 조건: -20 °C · -20°C
용해도: 2 O: · H2O: 10 mg/mL at 20 °C, 투명, 무색
물리적 상태: 흰색 고체
색상: 백색 결정체
냄새: 냄새 없는
수용성: 20 °C에서 · 20°C에서 10g/l
Merck: 13 · 13,2052
BRN: 5842642 · 5842642
InChIKey: GUQQBLRVXOUDTN-PPDWFABINA-N
SMILES: [H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O

화학적 성질

Chapso is a white crystalline powder. It is a zwitterionic detergent similar to Chaps, however, Chapso is more soluble and particularly better for the solubilization of integral membrane proteins.

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H315 (98%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (98%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (98%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 1건

1-Propanaminium, 2-hydroxy-N,N-dimethyl-3-sulfo-N-3-(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-ylaminopropyl-, inner salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesSkin Irrit. 2 (98%)；Eye Irrit. 2 (98%)；STOT SE 3 (98%)

규제 정보

Regulatory Information · 1건

1-Propanaminium, 2-hydroxy-N,N-dimethyl-3-sulfo-N-3-(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-ylaminopropyl-, inner salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

안전 데이터

wgk: 3
HS 번호: 2924297099
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36
F 고인화성물질: 3-10
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 1건

Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties.

응용 분야

용도Chapso is a nondenaturing biological detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

일반 설명CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]

郑州阿尔法化工有限公司+86-18530059196 · [email protected]

湖南腾峪新材料有限公司1822-9738810 18229738810 · [email protected]

연결된 노트

불러오는 중…

3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulfonate

기본 정보