Thiodiglycol → Deoxycholic Acid

HRID 1296194

반응식

HRID 1296194 반응식
C(O)CS[CH2:4][CH2:5][OH:6].CC(CC([C:16]1[CH:21]=[CH:20][C:19](OCCOCCO)=[CH:18][CH:17]=1)(C)C)(C)C.CCCCCCCCCCCC[O:41]CCO.[CH3:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][O:57][S:58]([O-:61])(=[O:60])=[O:59].[Na+:62].[CH3:63][C@@H:64]([C@@H:84]1[C@@:88]2(C)[C@@H:89]([OH:104])[CH2:90][C@@H:91]3[C@@:96]4([CH3:102])[CH2:97][CH2:98][C@@H](O)C[C@H:95]4C[C@@H](O)[C@H]3[C@@H:87]2CC1)[CH2:65][CH2:66][C:67](NCCC[N+](CC(O)CS([O-])(=O)=O)(C)C)=[O:68]>>[CH3:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][O:57][S:58]([O-:61])(=[O:60])=[O:59].[Na+:62].[CH3:63][C@@H:64]([C@@H:84]1[C@@:88]2([CH3:87])[C@@H:89]([OH:104])[CH2:90][C@@H:91]3[C@@:96]4([CH3:102])[CH2:97][CH2:98][C@@H:5]([OH:6])[CH2:4][C@H:95]4[CH2:18][CH2:17][C@H:16]3[C@@H:21]2[CH2:20][CH2:19]1)[CH2:65][CH2:66][C:67]([OH:68])=[O:41]

참가 물질

7

반응물 5

HCID 5447ThiodiglycolHCID 247502-(Dodecyloxy)ethanolHCID 24775Poly(oxy-1,2-ethanediyl), alpha-((1,1,3,3-tetramethylbutyl)phenyl)-omega-hydroxy-, potassium salt (1:1)HCID 1221453-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulfonateHCID 3423265Sodium Lauryl Sulfate

생성물 2

HCID 222528Deoxycholic AcidHCID 3423265Sodium Lauryl Sulfate

실험 절차

The FIG. 7 shows the results. The samples were loaded on the gels in the following order (from left to right) lane-1 control sample, lane 2-3 thiodiglycol, lane 4-5 Tween-20, lane 6-7 NP-40, lane 8-9 Brij-35, lane 10 SDS, lane 11 CHAPSO, 12-13 Triton-X100, lane 14 CHAP and lane 15 control. The electrophoresis results shows (after a comparison of several typical runs) that, with exception of SDS and de-oxycholate treated protein samples, most protein samples containing detergent showed batch to batch variation in protein precipitation yield. The protein precipitation yield depended on the techniques used for harvesting the precipitated protein. There were occasions when the precipitation yield of duplicate samples varied between 100% to 50%. Protein samples containing SDS invariably showed substantially 100% yield in multiple tests.

출처 및 근거

ORD 기록
ord-f27bc0fc73334de58d4f85664daabf79
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07244828B2

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