안지오텐신II,des-Phe(8)-

Angiotensin-(1-7)

HCID 123805

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 39386-80-6
표준 SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O
InChIKey: PVHLMTREZMEJCG-GDTLVBQBSA-N
분자식: C41H62N12O11
평균 분자량: 899 g/mol
단동위원소 질량: 898.46610084

이름 및 식별자

우선 이름: Angiotensin-(1-7)
IUPAC: (2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid
현지명: 안지오텐신II,des-Phe(8)-
영어명: angiotensin II, des-Phe(8)-
분자식: C41H62N12O11
분자량: 899.00478

이름 및 동의어

Angiotensin (1-7)angiotensin-(1-7)TXA127TXA-127ang 1-7(2S)-1-((2S)-2-(((2S,3S)-2-(((2S)-2-(((2S)-2-(((2S)-2-(((2S)-2-amino-4-hydroxy-4-oxobutanoyl)amino)-5-(diaminomethylideneamino)pentanoyl)amino)-3-methylbutanoyl)amino)-3-(4-hydroxyphenyl)propanoyl)amino)-3-methylpentanoyl)amino)-3-(3H-imidazol-4-yl)propanoyl)pyrrolidine-2-carboxylic acid(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-hydroxy-4-oxobutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(3H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxylic acidRefChem:55808051833-78-4angiotensin 1-7ASP-ARG-VAL-TYR-ILE-HIS-PROAngiotensin i (1-7)

이름 더 보기

안지오텐신II,des-Phe(8)-angiotensin II, des-Phe(8)-Angiotensin ii, des-phenylalanine(8)-Angiotensin ii, 8-de-L-phenylalanine-(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxylic acid

Angiotensin II (1-7) heptapeptideangiotensin II (1-7)Ang-(1-7)8-Des-phe-angiotensin IITalfirastide39386-80-6MFCD00153513Ile(5)-angiotensin II (1-7)

데이터베이스 식별자

CAS: 39386-80-6、51833-78-4
PubChem CID: 123805
ChEMBL: CHEMBL3545347
ChEBI: CHEBI:55438
Nikkaji: J285.101F

물성

구조 계산 물성

XLogP: -3
극성 표면적: 380 Å²
수소 결합 공여자 수: 12
수소 결합 수용자 수: 14
회전 가능 결합 수: 25
무거운 원자 수: 64
형식 전하: 0
복잡도: 1,660

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Drugs used to cause dilation of the blood vessels.

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