2,2,6,6-Tetramethyl-4-piperidone (HCID 13220)

이름 및 식별자

우선 이름: 2,2,6,6-Tetramethyl-4-piperidone
IUPAC: 2,2,6,6-tetramethylpiperidin-4-one
현지명: 오도라틴 (Odoratine)
영어명: Triacetonamine
분자식: C9H17NO
분자량: 155.24

이름 및 동의어

Triacetonamine826-36-82,2,6,6-Tetramethyl-4-piperidoneVincubineTempidonTMPoneDTXSID40415272K4430S3XPNSC-16579IKH-19DTXCID2021527RefChem:891346

이름 더 보기

오도라틴 (Odoratine)TEMPTAATETRAMETHYLPIPERIDINONETRIACETONEAMINEDL-22,2,6,6-Tetramethylpiperidone2,2,6,6-tetramethyl-4-piperidon

2,2,6,6-tetramethylpiperidone-4-toluene-p-sulfonate212-554-22,2,6,6-tetramethylpiperidin-4-oneTriacetonamin2,2,6,6-Tetramethyl-4-piperidinoneTriacetone amineVincubina2,2,6,6-Tetramethyl-4-oxopiperidine

데이터베이스 식별자

CAS: 826-36-8
PubChem CID: 13220
DTXSID: DTXSID4041527
ChEMBL: CHEMBL117614
ChEBI: CHEBI:177813
UNII: 2K4430S3XP
EC Number: 212-554-2
Nikkaji: J107D

물성

구조 계산 물성

XLogP: 0.5
극성 표면적: 29.1 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 11
형식 전하: 0
복잡도: 164

실험 및 물리화학적 성질

Melting Point34.9 °C

Physical DescriptionSolid

Dissociation Constants7.9

물리화학적 성질

녹는점: 59 · 59-61 °C
끓는 점: 105 · 105-105°C/18mm
밀도: 0.9796 · 0.9796 (rough estimate)
굴절률: 1.468 · 1.4680 (estimate)
인화점: 73 °C · 73°C
저장 조건: 2 · 2-8°C
용해도: DMSO및메탄올에 용해됨
산도 계수 (pKa): 9.2 · 9.20±0.60(Predicted)
물리적 상태: 고체
색상: 옅은 오렌지색에서 밝은 갈색까지
수용성: 249 g/L · 249g/L at 20℃
InChI: 1S/C9H17NO/c1-8(2)5-7(11)6-9(3,4)10-8/h10H,5-6H2,1-4H3
InChIKey: JWUXJYZVKZKLTJ-UHFFFAOYSA-N
SMILES: CC1(C)CC(=O)CC(C)(C)N1
LogP: 1.32 at · 1.32 at 25℃
NIST: 4 · 4-Piperidinone, 2,2,6,6-tetramethyl-(826-36-8)
EPA: 4 · 4-Piperidinone, 2,2,6,6-tetramethyl- (826-36-8)

화학적 성질

white crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H290 (77.1%): May be corrosive to metals [Warning Corrosive to Metals]；H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (79.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H315 (20.8%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (79.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H318 (77.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (20.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (20.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H412 (79.2%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P234, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P363, P390, P403+P233, P405, P406, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 192 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 13-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/14410

2,2,6,6-Tetramethyl-4-piperidone: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 2건

Met. Corr. 1 (77.1%)；Acute Tox. 4 (100%)；Skin Corr. 1B (79.2%)；Skin Irrit. 2 (20.8%)；Skin Sens. 1 (79.2%)；Eye Dam. 1 (77.1%)；Eye Irrit. 2 (20.8%)；STOT SE 3 (20.3%)；Aquatic Chronic 3 (79.2%)

Acute toxicity (Oral) - Category 4；Skin corrosion/irritation - Category 1；Serious eye damage/eye irritation - Category 1；Skin sensitization - Category 1；Specific target organ toxicity - Single exposure - Category 2 (cardiovascular system, nervous system)

규제 정보

Regulatory Information · 2건

Status: Active Update: 13-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/14410

2,2,6,6-Tetramethyl-4-piperidone: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 2
tsca: TSCA listed
rtecs: TO0127900
HS 번호: 29333990
risk_code: 34-22-36/37/38
hazard_code: C,Xn
safety_code: 45-36/37/39-26-22-36/37
기존화학 물질: 2004-3-2651
Hazard Classifications: Acute Tox. 4 OralAquatic Chronic 3Eye Dam. 1Met. Corr. 1Skin Corr. 1BSkin Sens. 1A
스토리지 클래스: 8B - Non-combustible corrosive hazardous materials

화학 및 산업

약리 정보

Cellular LocationsCytoplasm；Extracellular

용도 및 제조

General Manufacturing Information4-Piperidinone, 2,2,6,6-tetramethyl-: ACTIVE

응용 분야 · 2건

개요Triacetonamine (CAS 826-36-8), also known as 2,2,6,6-tetramethyl-4-piperidone or TAA, is a key intermediate in the synthesis of HALS (hindered amine light stabilisers); Their ability to effectively inhibit polymer degradation by scavenging free radicals is based on their sterically hindered amine functional groups, which are capable of forming stable N-oxides as active intermediates (the Denysov cycle). TAA is also used in the synthesis of pharmaceuticals, piperidine nitroso radicals and pyrrolidone derivatives. For example, the oxidation of TAA or its derivatives yields the corresponding tetramethylpiperidine-N-oxide, namely TEMPO; the latter can be used as a polymerisation inhibitor, molecular weight regulator or oxidation catalyst[2].

용도2,2,6,6-Tetramethyl-4-piperidinone (cas# 826-36-8) is a compound useful in organic synthesis.

상·하류 제품 정보

상류 원료

4-Heptanone, 2,6-diamino-2,6-dimethyl-22446-펜타메틸-2345-테트라히드로피리미딘 2,2,6,6-테트라메틸-4-피페리돈옥심 2,3-Dimethyl-2,3-dinitrobutane

하류 제품

트리아세톤디아민 2,2,6,6-테트라메틸피페리딘 2,2,4,4,6-pentamethyl-hexahydropyrimidine 1 2 2 6 6-Pentamethyl-4-piperidone 97 4-Amino-4-methyl-2-pentanone hydrogenoxalate N-부틸트리아세톤디아민 2,2,6,6-사메틸-4-피페리디놀

공급사50 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

河南国生化工有限公司17610068021 · [email protected]

河北展药生物科技有限公司15369953316 +8615369953316 · [email protected]

T&W GROUP021-61551611 13296011611 · [email protected]

爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

연결된 노트

불러오는 중…

오도라틴 (Odoratine)

기본 정보