1-[[(9H-플로렌-9-일메톡시)카보닐]옥시]-2,5-필롤리딘디온

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

HCID 134122CAS 82911-69-1
부분 구조 검색유사 구조 찾기

기본 정보

표준 SMILES
O=C(OCC1c2ccccc2-c2ccccc21)ON1C(=O)CCC1=O
InChIKey
WMSUFWLPZLCIHP-UHFFFAOYSA-N
분자식
C19H15NO5
평균 분자량
337.3 g/mol
단동위원소 질량
337.09502258

개요

used in the preparation of Fmoc-amino acids

이름 및 식별자

우선 이름
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
IUPAC
(2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
현지명
1-[[(9H-플로렌-9-일메톡시)카보닐]옥시]-2,5-필롤리딘디온
영어명
Fmoc-OSu
분자식
C19H15NO5
분자량
337.33

이름 및 동의어

82911-69-1N-(9-Fluorenylmethoxycarbonyloxy)succinimideFmoc-onsu9-Fluorenylmethylsuccinimidyl carbonateAD7AUS3GKTDTXSID902320902,5-PYRROLIDINEDIONE, 1-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]OXY]-2,5-Pyrrolidinedione, 1-(((9H-fluoren-9-ylmethoxy)carbonyl)oxy)-RefChem:926928DTXCID90154581433-520-5Fmoc-OSu
이름 더 보기
1-[[(9H-플로렌-9-일메톡시)카보닐]옥시]-2,5-필롤리딘디온(CASNo.82911-69-1)1-[[(9H-플로렌-9-일메톡시)카보닐]옥시]-2,5-필롤리딘디온Fomc-OsuFMOC-SU2,5-dioxopyrrolidin-1-yl 9H-fluoren-9-ylMethyl carbonateFMOC-Succinimide
Fmoc N-hydroxysuccinimide ester9-Fluorenylmethyl succinimidyl carbonate(9H-fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate(2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate9-Fluorenylmethyl N-succinimidyl carbonateN-(9-Fluorenylmethoxycarbonyloxy) succinimideMFCD00010733C19H15NO5

데이터베이스 식별자

CAS
82911-69-1
PubChem CID
134122
DTXSID
DTXSID90232090
UNII
AD7AUS3GKT
EC Number
433-520-5、617-400-1
Nikkaji
J208.522D

물성

구조 계산 물성

XLogP
2.7
극성 표면적
72.9 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
5
회전 가능 결합 수
5
무거운 원자 수
25

물리화학적 성질

녹는점
150 · 150-153 °C(lit.)
끓는 점
150 · 150-153°C
밀도
1.346 · 1.3460 (rough estimate)
굴절률
1.5 · 1.5000 (estimate)
저장 조건
2 · 2-8°C
용해도
디메틸 설폭시드 및 디메틸 포름아미드에 용해됩니다.

화학적 성질

White powder

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P321, P330, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Warning

H302 (98.8%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P321, P330, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

유해성 정보

Regulatory Information · 2건

Status: Active Update: 29-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13924

2,5-Pyrrolidinedione, 1-(9H-fluoren-9-ylmethoxy)carbonyloxy-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 4건

Acute Tox. 4 (100%)

Acute Tox. 4 (98.8%)

Acute toxicity - category 4

Acute Tox. 4 *

안전 데이터

wgk
3
ridadr
UN 3077 9 / PGIII
HS 번호
29251995
risk_code
36/37/38-51/53-43-22
hazard_code
Xi,N,Xn
safety_code
22-24/25-26/37/39-26-61-37-24

화학 및 산업

응용 분야 · 2건

개요Fmoc-OSu (N-(9-Fluorenylmethoxycarbonyloxy)succinimide) is a reagent used in solid-phase peptide synthesis (SPPS) for Fmoc protection of amino groups, particularly amino acids. This reagent contains an Fmoc functional group, which is stable under acidic conditions and cleaves under alkaline conditions. Fmoc-OSu reacts with amino groups to form stable amide bonds, helping to reduce the occurrence of side reactions. Additionally, Fmoc-OSu can also be used as a fluorescent reagent.

용도N-(9-Fluorenylmethoxycarbonyloxy)succinimide is used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.

상·하류 제품 정보

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
成都市久鼎化学技术有限公司18584079237 · [email protected]

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