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글리시딜메틸에테르

1,2-Epoxy-3-methoxypropane

HCID 13589
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기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
930-37-0
표준 SMILES
COCC1CO1
InChIKey
LKMJVFRMDSNFRT-UHFFFAOYSA-N
분자식
C4H8O2
평균 분자량
88.11 g/mol
단동위원소 질량
88.0524295

개요

Methyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

이름 및 식별자

우선 이름
1,2-Epoxy-3-methoxypropane
IUPAC
2-(methoxymethyl)oxirane
현지명
글리시딜메틸에테르
영어명
GLYCIDYL METHYL ETHER
분자식
C4H8O2
분자량
88.11

이름 및 동의어

Glycidyl methyl ether930-37-0Methyl glycidyl etherOxirane, (methoxymethyl)-1,2-EPOXY-3-METHOXYPROPANEGlycidol methyl ether(Methoxymethyl)oxiraneMethylglycidyl ether3-Methoxypropylene oxide3-Methoxy-1,2-epoxypropanePropane, 1,2-epoxy-3-methoxy-2,3-Epoxypropyl-methyl ether
이름 더 보기
글리시딜메틸에테르2-(Methoxymethyl)oxiraneoxirane,(methoxymethyl)-Epiol MEpimethylinDenacol EX-131glycidolmethylethermethylglycidylether
Oxirane, 2-(methoxymethyl)-NSC 86950CCRIS 2630HSDB 5444EINECS 213-216-7BRN 010250587MK2KA66TAI3-52869

데이터베이스 식별자

CAS
930-37-0
PubChem CID
13589
DTXSID
DTXSID9025613
UNII
87MK2KA66T
EC Number
213-216-7
Nikkaji
J60.714B

물성

구조 계산 물성보충 중

XLogP
-0.2
극성 표면적
21.8 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
2
회전 가능 결합 수
2
무거운 원자 수
6
형식 전하
0
복잡도
44.8

실험 및 물리화학적 성질

PolymersPlastics & Rubber -> Glycidyl Ethers
LogP0.03
Solubilitygreater than or equal to 100 mg/mL at 68.9 °F (NTP, 1992)
Flash Point · 2건

less than 69 °F (NTP, 1992)

Flash point < 21 °C

Physical Description · 2건

Methyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

Colorless liquid; [CAMEO]

물리화학적 성질

끓는 점
110 °C · 110°C
밀도
0 · 0,98 g/cm3
굴절률
1.408 · 1.4080-1.4140
인화점
24 °C · 24°C
저장 조건
Refrigerator
용해도
클로로포름(약간 용해됨), 톨루엔(약간 용해됨)
물리적 상태
기름
색상
무색
InChI
InChI=1S/C4H8O2/c1-5-2-4-3-6-4/h4H,2-3H2,1H3
InChIKey

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

Danger

H225 (75%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

유해성 정보

DOT LabelFlammable Liquid Poison
Fire HazardsThis chemical is flammable. (NTP, 1992)
Health HazardsExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Hazards SummaryA mutagen and primary irritant; Caused lacrimation and somnolence in lethal-dose feeding studies of rats; [RTECS] Emergency treatment: irritants; [HSDB] An irritant; [MSDSonline]
Reactive GroupEthers
Reactivity AlertsHighly Flammable
Reactivity Profile · 1건

METHYL GLYCIDYL ETHER, an ether can act as a base. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

화학 및 산업

용도 및 제조

Uses · 2건

Used as a research chemical; Not commercially produced in the US; [HSDB]

RESEARCH CHEMICAL

U.S. Exports · 2건

(1979) No Data

(1981) No Data

U.S. Imports · 2건

(1979) No Data

(1981) No Data

U.S. Production · 2건

(1979) NOT PRODUCED COMMERCIALLY IN U.S.

(1981) NOT PRODUCED COMMERCIALLY IN U.S.

Methods of ManufacturingPROBABLY BY REACTION OF 1-CHLORO-2-HYDROXY-3-METHOXYPROPANE WITH SODIUM HYDROXIDE
General Manufacturing InformationOxirane, 2-(methoxymethyl)-: ACTIVE

응용 분야

용도2-(Methoxymethyl)oxirane is used in the fixation of biological tissues or in collagen bioprosthetic fixation processes.

일반 설명Clear colorless liquid.

상·하류 제품 정보

상류 원료

디클로로프로펜trans-1,3,3-Trichloro-1-propene1,2,2-트리클로로프로판1-Propene, 1,3,3-trichloro-, (Z)-(1E)-1,2,3-트리클로로-1-프로펜

관련 반응

27건
반응 기록 만들기
HRID 25038 반응식
HRID 25038반응물로uspto-grants-2005_02
HRID 74864 반응식
HRID 74864반응물로uspto-grants-2014_09
HRID 74933 반응식
HRID 74933반응물로uspto-grants-2014_09
HRID 108013 반응식
HRID 108013반응물로Training data from https://doi.org/10.1039/C8SC04228D (2/10)
HRID 144630 반응식
HRID 144630반응물로Training data from https://doi.org/10.1039/C8SC04228D (9/10)
HRID 184045 반응식
HRID 184045반응물로Training data from https://doi.org/10.1039/C8SC04228D (6/10)
HRID 245517 반응식
HRID 245517반응물로uspto-grants-2014_02
HRID 321093 반응식
HRID 321093반응물로Training data from https://doi.org/10.1039/C8SC04228D (8/10)
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더보기
새 노트새 반응견적 요청하기
LKMJVFRMDSNFRT-UHFFFAOYSA-N
SMILES
O1CC1COC
EPA
Methyl glycidyl ether (930-37-0)
Air and Water Reactions
Highly flammable. May be sensitive to exposure to air(peroxide formation). (NTP, 1992). Water soluble.
Hazard Classes and Categories · 2건

Flam. Liq. 2 (75%)

Flammable liquids - Category 2

안전 및 보호

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

독성 정보

Non-Human Toxicity Excerpts · 3건

...THEY ARE VERY IRRITATING TO EYES, SKIN, & RESPIRATORY TRACT. /GLYCIDYL ETHERS/

1,2-EPOXY-3-METHOXYPROPANE WAS MUTAGENIC IN KLEBSIELLA PNEUMONIAE.

TOPICAL APPLICATION OF 0.1 ML ALIQUOT OF 1,2-EPOXY-3-METHOXYPROPANE TO CLIPPED & DEPILATED BACKS OF GUINEA PIGS 4 TIMES IN 10 DAYS. AFTER 2 WK REST PERIOD, GUINEA PIGS WERE CHALLENGED ON THE CLIPPED FLANKS. TWO OF THE 49 GUINEA PIGS TESTED BECAME SENSITIZED.

안전 데이터

tsca
TSCA listed
rtecs
TZ3530000
ridadr
3271
HS 번호
2909200090
risk_code
10
safety_code
16
포장분류
II
위험 등급
3.1
유해 물질 데이터
930-37-0(Hazardous Substances Data)
2-CHLORO-2-PROPEN-1-OL
클로로아세톤
시스-1,3-디클로로-1-프로펜
1,1,2-트리클로로프로판
아크롤레인
알릴 알코올
디클로로프로펜
3-클로로-1-프로판올
1,1,3-트리클로로프로펜
에피클로로하이드린
디브로모클로로메탄
에폭시헥산(1,2-)
아세트알데히드