Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
안터간
안터간 · PM-245 · Bridal · Antergan · Lergitin · Fourneau compound-2339RP · benzyl-(2-dimethylaminoethyl)-phenyl-amine · N',N'-dimethyl-N-phenyl-N-(phenylmethyl)ethane-1,2-diamine
식별자 및 물리적 특성
| CAS No. | 961-71-7 |
|---|---|
| 분자식 | C17H22N2 |
| 평균 분자량 | 254.37 g/mol |
| 단동위원소 질량 | 254.17829871 g/mol |
| SMILES | CN(C)CCN(Cc1ccccc1)c1ccccc1 |
| InChIKey | CHOBRHHOYQKCOU-UHFFFAOYSA-N |
| PubChem CID | 13751 |
| ChEMBL | CHEMBL157118 |
| ChEBI | CHEBI:135041 |
| DTXSID | DTXSID3043863 |
| 현지명 | 안터간 |
화학 및 물리적 성질
| XLogP | 3.7 |
|---|---|
| 극성 표면적 | 6.5 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 6 |
| 무거운 원자 수 | 19 |
| 형식 전하 | 0 |
| 복잡도 | 227 |
| 밀도 | 1.019 (NTP, 1992) - Denser than waterwill sink1.0160 |
| 끓는 점 | 354 to 356 °F at 7 mmHg (NTP, 1992)387.59°C (rough estimate) |
| Physical Description | Phenbenzamine is a liquid. (NTP, 1992) |
| 굴절률 | 1.5794 |
| 색상 | 담황색 오일 |
| EPA | Phenbenzamine (961-71-7) |
안전 및 규제
| 건강 유해성 | ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products. (NTP, 1992) |
|---|---|
| 반응성 그룹 | Amines, Phosphines, and Pyridines |
| Reactivity Profile | PHENBENZAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| Air and Water Reactions | No rapid reaction with air. No rapid reaction with water. |
| 소화 | This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. (NTP, 1992) |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 비화재 누출 대응 | SMALL SPILLS AND LEAKAGE: Dampen spilled material with toluene to avoid dust, then transfer material to a suitable container. Use absorbent paper dampened with toluene to pick up remaining material. Wash surfaces well with soap and water. Seal all waste in vapor-tight plastic bags for eventual disposal. |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992) |
| 독성 | LDLo ipr-rat: 120 mg/kg BJPCAL 11,1,56 |
용도
역사
In 1942 phenbenzamine (Antergan), C17H22N2, was the first antihistamine to be successfully used in humans.
일반 설명
Liquid.