기본 정보
- 표준 SMILES
Cc1c(C(=O)O)c(O)cc2c1C(=O)c1c(O)c([C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(O)c(O)c1C2=O- InChIKey
DGQLVPJVXFOQEV-NGOCYOHBSA-N- 분자식
- C22H20O13
- 평균 분자량
- 492.4 g/mol
- 단동위원소 질량
- 492.09039069
이름 및 식별자
- 우선 이름
- Carmine
- IUPAC
- 3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[(2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracene-2-carboxylic acid
- 현지명
- 카바민 산
- 영어명
- Carminic Acid
- 분자식
- C22H20O13
- 분자량
- 492.39
이름 및 동의어
Carmine1390-65-4B Rose liquid3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-[(2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]anthracene-2-carboxylic acidCarmine (Coccus cacti L.)Cochineal (Coccus cacti L.)Cochineal DyeDye, Cochineal3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-7-((2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)anthracene-2-carboxylic acidRefChem:574680DTXSID20442167-glucopyranosyl-3,5,6,8-tetrahydroxyl-1-methyl-9,10-dioxoanthracene-2-carboxylic acid
이름 더 보기
카르바민산카바민산카바민산CI 75470E120coccinic acidCARMINE ALUMINUM LAKECarminicC.I.Naturalred4NSC 326224CARMINE 2GCARMINE 40
215-724-4Carmine RedST0693397-[(5S,2R,3R,4R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydropy ran-2-yl)]-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxoanthracene-2-carboxylic aci dNSC326224NCGC00091708-04SCHEMBL34094orb1218979
데이터베이스 식별자
- CAS
1260-17-9、1390-65-4- PubChem CID
- 14749
- ChEMBL
CHEMBL1366408- EC Number
- 215-724-4
- Nikkaji
- J3.366I
물성
구조 계산 물성
- XLogP
- 0.5
- 극성 표면적
- 243 Ų
- 수소 결합 공여자 수
- 9
- 수소 결합 수용자 수
- 13
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 35
- 형식 전하
- 0
- 복잡도
- 864
실험 및 물리화학적 성질
Physical DescriptionRed crystals in methanol; bright red powder; deep red color in water; [HSDB]
물리화학적 성질
- 녹는점
- 136 °C · 136 °C
- 끓는 점
- 506.2 °C · 506.2°C (rough estimate)
- 밀도
- 1.4504 · 1.4504 (rough estimate)
- 굴절률
- 1.6 · 1.6000 (estimate)
- 인화점
- 12 ℃ · 12℃
- 저장 조건
- room temp
- 용해도
- 30 g/L · 30g/L
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 1.62 · 1.62±0.20(Predicted)
- 색상
- 빨간색에서 진한 빨간색까지
- 수소이온지수(pH)
- 1.6 · 1.6 (10g/l, H2O, 20℃)
- 냄새
- 냄새 없는
- 수용성
- 1.298 g/L · 1.298g/L(상온)
- Merck
- 14 · 14,1843
- BRN
- 71651 · 71651
- 주요 응용
- 진단 검사 제조혈액학조직학
- InChIKey
- DGQLVPJVXFOQEV-JNVSTXMASA-N
- SMILES
- Cc1c(C(O)=O)c(O)cc2C(=O)c3c(O)c(O)c([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c3C(=O)c12
- LogP
- 1.532 · 1.532 (est)
- EPA
- 4 · C.I. Natural Red 4 (1260-17-9)
화학적 성질
Cochineal extract is a concentrated solution obtained after removing alcohol from an aqueous–alcoholic extract of cochineal (Dactylopius coccus Costa, also called Coccus cati L.). This extract is used as a color additive, the primary colorant being carminic acid.
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (298 of 298) of all reports.
Not Classified；Reported as not meeting GHS hazard criteria by 298 of 298 companies. For more detailed information, please visit ECHA C&L website.
Aggregated GHS information provided per 298 reports by companies from 1 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 298 of 298 reports by companies.；There are 0 notifications provided by 0 of 298 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
유해성 정보
Regulatory Information
Chemical: Carmine
Status: Active Update: 13-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/28382
Carmine: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Anthraquinones are toxic by ingestion and may cause vomiting, diarrhea, kidney and liver damage, and coma; Deaths have been reported after children ingested Rhamnus berries; [HSDB] Occupational asthma confirmed in workers in dye manufacturing plant; [Malo] Cochineal is the dried bodies of the female insect coccus cacti. Carminic acid is the active coloring material, and carmine is the aluminum lake of carminic acid. [HSDB] See Carminic acid and Cochineal.
Hazard Classes and CategoriesNot Classified
독성 정보
Adverse Effects
Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.；Asthma - Reversible bronchoconstriction (narrowing of bronchioles) initiated by the inhalation of irritating or allergenic agents.
규제 정보
Regulatory Information
Chemical: Carmine
Status: Active Update: 13-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/28382
Carmine: Does not have an individual approval but may be used under an appropriate group standard
안전 데이터
- wgk
- 2
- tsca
- TSCA listed
- HS 번호
- 32129000
- safety_code
- 22-24/25
- 기존화학 물질
- KE-17707
- 스토리지 클래스
- 11 - Combustible Solids
- 유해 물질 데이터
- 1260-17-9(Hazardous Substances Data)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Natural or synthetic dyes used as coloring agents in processed foods.
Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
용도 및 제조
Uses
Used in inks, dyes, food coloring, photography, paints, microbiological stains, and chemical reagents; [HSDB] Carmine is used as a microscopic stain of chromatin. [Ullmann]
Painting (Pigments, Binders, and Biocides) [Category: Paint]；Photographic Processing [Category: Other]；Textiles (Printing, Dyeing, or Finishing) [Category: Industry]
Household Products
Information on 77 consumer products that contain Carmine in the following categories is provided:；• Personal Care
Information on 2 consumer products that contain C.I. 75470 in the following categories is provided:；• Personal Care
Use ClassificationCosmetics -> Cosmetic colorant
응용 분야
역사CI Natural Red 4(CI 75470), is a red dye occurring as a glycoside in the body of the cochineal insect Dactylopius coccus of the order Homoptera, family Coccidae. This insect is native to Central and South America. The Aztecs had extracted the dye from the insect centuries before the coming of the Spaniards. For breeding purposes, the insects were collected in the autumn and carefully protected during the winter months. Cochineal was harvested after three months, and then the bugs were killed by immersion in hot water, by placing in hot ovens, or by exposure to the hot sun. The latter method produced the highest quality dye. At present, Peru and the Canary Islands are the main source of the dye. Until the advent of synthetic dyes, the principal use for carminic acid was for dyeing tin-mordanted wool or silk. Its aluminum lake, carmine, finds use in the coloring of foods.
용도Carminic acid (C.I. 75470) For staining nuclei in histological sections. Used to prepare staining solutions. CAS 1260-17-9, pH 1.6 (10g/l, HO, 20°C).
일반 설명Dark purplish-brown mass or bright red or dark red powder. Darkens at 248°F. Deep red color in water. Yellow to violet in acidic aqueous solutions.
상·하류 제품 정보
하류 제품
공급사50 곳
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
上海纽雀客生物科技有限公司13916276291 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
广东云星生物技术有限公司0751-18902340975/189023400307 18902340307 · [email protected]
Nanjing Duly Biotech Co.,Ltd+86-18013301590 · [email protected]
武汉市皇臻生物化工有限公司13795480948 · [email protected]
佛山宝诺生物科技有限公司0757-85921206 18520245316 · [email protected]
湖北成海化工有限公司027-59220433 18327245847 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
北京伊诺凯科技有限公司400-810-7969 010-59572699 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
南京杜莱生物技术有限公司025-84699383-8003;025-846993838003-8003 18013301590 · [email protected]
上海陶素生化科技有限公司021-33632979 · [email protected]
PT CHEM GROUP LIMITED+86-85511178; +86-85511178 · [email protected]
天津阿尔塔科技有限公司022-65378550-8551 · [email protected]
成都零六生物科技有限公司400-1166-196 13458535857 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
青岛海智微元生物科技有限公司18317699790 18317699790 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
桦特昇生物科技（武汉）有限公司027-59207879 1972026995 18140587686 · [email protected]
天津阿尔塔科技有限公司022-6537-8550 15522853686 · [email protected]
武汉天植生物技术有限公司18607101326 15172504745 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
九鼎化学（上海）科技有限公司4009209199 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
广东翁江化学试剂有限公司0751-2886766 13927870850 · [email protected]
艾吉析科技（上海）有限公司17721401538;17717235263 17721401538 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
武汉福鑫化工有限公司+86-2759207851; +86-18007136271 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
山东西亚化学有限公司4009903999 13395398332 · [email protected]
广州市金华大化学试剂有限公司020-84383047 · [email protected]
上海贤鼎生物科技有限公司021-021-52271985 17721149837 · [email protected]
추가 설명
정의ChEBI: A tetrahydroxyanthraquinone that is that is 1,3,4,6-tetrahydroxy-9,10-anthraquinone substituted by a methyl group at position 8, a carboxy group at position 7 and a 1,5-anhydro-D-glucitol moiety at position 2 via a C-gly osidic linkage. It is a natural dye isolated from several insects such as Dactylopius coccus.
관련 반응
1건
연결된 노트
불러오는 중…