기본 정보
- CAS
14281-83-5- 표준 SMILES
NCC(=O)[O-].NCC(=O)[O-].[Zn+2]- InChIKey
UOXSXMSTSYWNMH-UHFFFAOYSA-L- 분자식
- C4H8N2O4Zn
- 평균 분자량
- 213.5 g/mol
개요
The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Glycinate...
이름 및 식별자
- 우선 이름
- Zinc Glycinate
- IUPAC
- zinc bis(2-aminoacetate)
- 현지명
- 징크글라이시네이트
- 영어명
- Zinc glycinate
- 분자식
- C4H8N2O4Zn
- 분자량
- 213.51
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
14281-83-5- PubChem CID
- 151910
- DTXSID
DTXSID60162193- UNII
- 681VJX72FE
- EC Number
- 238-173-1
- Nikkaji
- J208.553D
물성
구조 계산 물성
- 극성 표면적
- 132 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 11
- 형식 전하
- 0
- 복잡도
- 37.4
실험 및 물리화학적 성질
물리화학적 성질
- 녹는점
- 300 °C · >300 °C (decomp)
- 밀도
- 851.3 · 851.3[at 20℃]
- 증기압
- 0 Pa · 0Pa at 25℃
- 용해도
- 물에 용해됨
- 물리적 상태
- powder to crystal
- 색상
- 흰색에서 거의 흰색
- 수용성
- 3.28 mg/L · 3.28mg/L at 23℃
- 주요 응용
- 펩타이드 합성
- 화장품 원료 기능
- 버퍼링
- InChI
- InChI=1S/2C2H5NO2.Zn/c2*3-1-2(4)5;/h2*1,3H2,(H,4,5);/q;;+2/p-2
- InChIKey
- UOXSXMSTSYWNMH-UHFFFAOYSA-L
- SMILES
- C(=O)(CN)O[Zn]OC(=O)CN
- LogP
- -3.21 at · -3.21 at 25℃
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 1.2% (2 of 163) of reports.
Danger
H302 (98.2%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 163 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
유해성 정보
Regulatory Information
Chemical: Zinc, bis(glycinato-N,O)-, (T-4)-
Regulation (EC) No 178/2002 (amended)
Status: Active Update: 09-07-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/32619
Zinc glycinate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Acute Tox. 4 (98.2%)
Acute toxicity - category 4
독성 정보
Toxicity Summary
The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Glycinate...
Safe for use in cosmetics, with qualifications
안전 데이터
- wgk
- WGK 3
- HS 번호
- 2922.49.8000
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
용도 및 제조
응용 분야
개요Zinc Glycinate features the 100% fully reacted TRAACS zinc bis-glycinate chelate. Zinc is essential for the development and proper functioning of the reproductive organs, including healthy prostate function, and has been shown to support healthy immune system function. Zinc also supports enzyme activity associated with tissue synthesis, energy metabolism, and bone mineralization. Zinc Glycinate is readily bioavailable and easily absorbed as an intact chelate. It is superior to other forms of zinc because it does not get ionized in the gut before absorption. Instead, it appears to be metabolized in the body right at the target tissue. Deficiencies in zinc can lead to an impaired immune system, decreased glucose metabolism, hormonal imbalance, and slower wound healing.
용도Zinc glycinate is used as a dietary supplement to maintain zinc levels in the body. Zinc is an essential mineral in the body and plays a vital role in cell development and gene expression. It has a variety of pharmacological effects such as antioxidant, anti-inflammatory, platelet activity enhancement, immunity boosting and digestive aid.
제조 방법
The preparation method of zinc glycinate comprises the following steps: (1) chelating a salt: adding glycine, basic zinc carbonate and water into a reaction kettle, stirring, heating to 70-90°C and making carbon dioxide overflow fully to generate zinc glycinate; and (2) drying: centrifugally dehydrating the obtained zinc glycinate, transferring into a fluidized bed and drying at the temperature of 100-120°C to obtain a zinc glycinate product.
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