Tenocyclidine hydrochloride (1:1)
GK 0 · CL-421 · Thienylcyclidine · Thienylphencyclidine · 1-[1-(2-Thienyl)cyclohexyl]piperidine Hydrochloride · 1-(1-thiophen-2-ylcyclohexyl)piperidine:hydrochloride
식별자 및 물리적 특성
| CAS No. | 1867-65-8 |
|---|---|
| 분자식 | C15H24ClNS |
| 평균 분자량 | 285.884 g/mol |
| 단동위원소 질량 | 285.13179845 g/mol |
| SMILES | Cl.c1csc(C2(N3CCCCC3)CCCCC2)c1 |
| InChIKey | IIPLEZRBGQCZMF-UHFFFAOYSA-N |
| PubChem CID | 16640802 |
| EC No. | 631-590-3 |
| DTXSID | DTXSID40904770 |
화학 및 물리적 성질
| 녹는점 | 233-236 °C |
|---|---|
| 용해도 | DMF: 5 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 2 mg/mlEthanol: 2 mg/mlMethanol: 1 mg/ml |
| 물리적 상태 | 결정성 고체 |
안전 및 규제
| 신호 어 | Danger |
|---|---|
| 유해·위험 문구 | 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H315 |
용도
개요
Tenocyclidine (TCP), known more formally as N-[1-(2-thienyl)cyclohexyl] piperidine, is an analog of phencyclidine (PCP) in which the phenyl substituent is replaced with a thiophene group. TCP is a potent antagonist of the NMDA receptor-gated ion channel (Kd = 9 nM). TCP blocks NMDA-activated excitatory postsynaptic potential in brain more potently than PCP. PCP and many analogs, including TCP, block the uptake and enhance the release of dopamine both in vitro and in vivo. TCP is regulated as a Schedule I compound in the United States. This product is intended for forensic and research applications.
용도
An analog of the hallucinogen Phencyclidine (P295500).