2-Hydroxy-1-naphthoic acid (HCID 16790)

이름 및 식별자

우선 이름: 2-Hydroxy-1-naphthoic acid
IUPAC: 2-hydroxynaphthalene-1-carboxylic acid
현지명: 2-히드록시-1-나프토산
영어명: 2-Hydroxy-1-naphthoic acid
분자식: C11H8O3
분자량: 188.18

이름 및 동의어

2-Hydroxy-1-naphthoic acid1-Naphthalenecarboxylic acid, 2-hydroxy-1-NAPHTHOIC ACID, 2-HYDROXY-E3H4QZ94UYNSC 2803NSC-2803EINECS 218-919-2UNII-E3H4QZ94UYAI3-19839DTXSID9062304RefChem:873421Naphthoic acid, 2hydroxy

이름 더 보기

2-하이드록시-1-나프토산AKOS 223-44RARECHEM AL BE 0092LABOTEST-BB LT004526442-HYDROXY-1-PHTHOIC ACID2-hydroxy-α-naphthoic acidNaphthol-1-carboxylic acid2-NAPHTHOL-1-CARBOXYLIC ACID2-Hydroxy-1-naphthoicAcid>

DTXCID10367591Naphthoic acid, 2hydroxy (8CI)1-Naphthoic acid, 2-hydroxy-(8CI)1Naphthalenecarboxylic acid, 2hydroxy218-919-2UPHOPMSGKZNELG-UHFFFAOYSA-N2283-08-12-hydroxynaphthalene-1-carboxylic acid

데이터베이스 식별자

CAS: 2283-08-1、30440-92-7
PubChem CID: 16790
DTXSID: DTXSID9062304
ChEMBL: CHEMBL2269234
UNII: E3H4QZ94UY
EC Number: 218-919-2、250-200-9
Nikkaji: J7.386E

물성

구조 계산 물성

XLogP: 2.9
극성 표면적: 57.5 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 3
회전 가능 결합 수: 1
무거운 원자 수: 14
형식 전하: 0
복잡도: 227

실험 및 물리화학적 성질

Physical DescriptionWhite powder; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: 167 °C · 167 °C (dec.) (lit.)
끓는 점: 283.17 °C · 283.17°C (rough estimate)
밀도: 1.21 · 1.2100 (rough estimate)
굴절률: 1.64 · 1.6400 (estimate)
저장 조건: Sealed in dry,Room Temperature
물리적 상태: powder to crystal
산도 계수 (pKa): 1 · pK1:3.29;pK2:9.68 (20°C)
색상: White to Light red to Green
BRN: 975575 · 975575
InChI: 1S/C11H8O3/c12-9-6-5-7-3-1-2-4-8(7)10(9)11(13)14/h1-6,12H,(H,13,14)
InChIKey: UPHOPMSGKZNELG-UHFFFAOYSA-N
SMILES: OC(=O)c1c(O)ccc2ccccc12
EPA: 1 · 1-Naphthalenecarboxylic acid, 2-hydroxy- (2283-08-1)

화학적 성질 · 1건

2-Hydroxy-1-naphthoic acid [2283-08-1], C11H8O3, Mr 188.17, has a mp of 156 – 157℃ (decomp. to 2-naphthol and CO2). The monosodium salt is unstable in hot aqueous solution. 2- Hydroxy-1-naphthoic acid is decarboxylated by nitrous acid, forming 1-nitroso-2-naphthol, and by diazo salts, forming a 1-azo-2-naphthol. An ethanolic solution of 2-hydroxy-1-naphthoic acid gives a dark blue color with iron(III) chloride. Chlorosulfonic acid at 30℃ gives the 6-sulfonyl chloride derivative.

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Chemical: 1-Naphthalenecarboxylic acid, 2-hydroxy-

1-Naphthalenecarboxylic acid, 2-hydroxy-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationEvaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia

Hazards SummaryA skin and strong eye irritant; [Alfa Aesar MSDS]

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (97.8%)

규제 정보

Regulatory Information · 2건

Chemical: 1-Naphthalenecarboxylic acid, 2-hydroxy-

1-Naphthalenecarboxylic acid, 2-hydroxy-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.