1,12-Dodecanediamine (HCID 17727)

이름 및 식별자

우선 이름: 1,12-Dodecanediamine
IUPAC: dodecane-1,12-diamine
현지명: 1,12-도데칸디아민
영어명: 1,12-Dodecanediamine
분자식: C12H28N2
분자량: 200.36

이름 및 동의어

1,12-Diaminododecane2783-17-71,12-DODECANEDIAMINEDodecamethylenediamineDodecyldiamine1,12-Dodecamethylenediamine1,12'-Dodecylenediamine1,12'-DodecamethylenediamineJ3LM80W9NTNSC-55050NSC-59861DTXSID2044636

이름 더 보기

1,12-도데칸디아민DODECANEDIAMINEN12N,N-12NDiaminododecane1,12-DODECANEDIAMERARECHEM AL BW 0116Decanethylenediamine

RefChem:410376DTXCID0024636220-489-6Dodecane-1,12-diamine1,12-DiamindodecaneN12NNSC 55050NSC 59861

데이터베이스 식별자

CAS: 2783-17-7
PubChem CID: 17727
DTXSID: DTXSID2044636
ChEMBL: CHEMBL69590
ChEBI: CHEBI:49385
UNII: J3LM80W9NT
EC Number: 220-489-6
Nikkaji: J42.964C

물성

구조 계산 물성

XLogP: 3
극성 표면적: 52 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 2
회전 가능 결합 수: 11
무거운 원자 수: 14
형식 전하: 0
복잡도: 82

실험 및 물리화학적 성질

Physical DescriptionAqueous solution (90% water); [Aldrich MSDS]

물리화학적 성질

녹는점: 67 · 67-69 °C(lit.)
끓는 점: 304 °C · 304°C
밀도: 0.8417 · 0.8417 (rough estimate)
증기압: 0.04 Pa · 0.04Pa at 25℃
굴절률: 1.4383 · 1.4383 (estimate)
인화점: 311 °F · 311 °F
저장 조건: Keep in dark place,Inert atmosphere,Room temperature
용해도: 에탄올에 용해됩니다.
물리적 상태: powder to lump
산도 계수 (pKa): 10.97 · 10.97±0.10(Predicted)
색상: 흰색에서 거의 흰색
수용성: 520 mg/L · 520mg/L at 19.5℃
BRN: 1742765 · 1742765
InChI: 1S/C12H28N2/c13-11-9-7-5-3-1-2-4-6-8-10-12-14/h1-14H2
InChIKey: QFTYSVGGYOXFRQ-UHFFFAOYSA-N
SMILES: NCCCCCCCCCCCCN
LogP: 2.2 at · 2.2 at 21℃
EPA: 1 · 1,12-Dodecanediamine (2783-17-7)

화학적 성질

WHITE CRYSTALLINE SOLID

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 7.1% (4 of 56) of reports.

Danger

H302 (92.9%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (82.1%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H315 (10.7%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (73.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H318 (12.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H331 (12.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]；H400 (10.7%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P332+P317, P333+P317, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 56 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 4 of 56 reports by companies.；There are 6 notifications provided by 52 of 56 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 28-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/29535；Status: Active Update: 31-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/25721

1,12-Dodecanediamine: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1건

A mild eye irritant; Causes hypermotility, weight loss, and respiratory depression in inhalation studies of rats; Causes inflammation of trachea and bronchi in 2-week intermittent inhalation studies of rats; [RTECS] Causes burns; May cause skin sensitization; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion; [Aldrich MSDS] See 1,8-Octamethylenediamine and 1,6-Diaminohexane.

Hazard Classes and CategoriesAcute Tox. 4 (92.9%)；Skin Corr. 1B (82.1%)；Skin Irrit. 2 (10.7%)；Skin Sens. 1B (73.2%)；Eye Dam. 1 (12.5%)；Acute Tox. 3 (12.5%)；Aquatic Acute 1 (10.7%)

독성 정보

Adverse EffectsDermatotoxin - Skin burns.

Toxicity DataLC50 (rat) = 680 mg/m3/4hr

규제 정보

Regulatory Information · 2건

Status: Active Update: 28-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/29535；Status: Active Update: 31-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/25721

1,12-Dodecanediamine: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 1
tsca: TSCA listed
rtecs: JR2200000
ridadr: UN 3259 8/PG 3
HS 번호: 29212900
risk_code: 22-34-43
hazard_code: C
safety_code: 26-36/37/39-45
위험 등급: 8
기존화학 물질: 2015-3-6730
Hazard Classifications: Acute Tox. 4 OralSkin Corr. 1BSkin Sens. 1
스토리지 클래스: 8A - Combustible corrosive hazardous materials

화학 및 산업

용도 및 제조

General Manufacturing Information1,12-Dodecanediamine: ACTIVE

응용 분야

용도Feedstock for polymer synthesis. Source of twelve carbon chain for medicinal drugs.1

상·하류 제품 정보

하류 제품

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

郑州阿尔法化工有限公司+86-18530059196 · [email protected]

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

추가 설명 · 2건

정의ChEBI: An alkane-alpha,omega-diamine that is dodecane substituted by amino groups at positions 1 and 12.

정의Diamines containing more than six carbon atoms can be obtained readily by hydrogenating the corresponding dinitriles over a Raney nickel catalyst in a batch procedure under pressure at up to 125 ℃. A five- to tenfold excess of liquid ammonia is used, with or without methanol solvent. Higher diamines can be prepared continuously, as described for the production of hexamethylenediamine.