4-포르밀모폴린

N-Formylmorpholine

HCID 20417CAS 4394-85-8

기본 정보

표준 SMILES
O=CN1CCOCC1
InChIKey
LCEDQNDDFOCWGG-UHFFFAOYSA-N
분자식
C5H9NO2
평균 분자량
115.13 g/mol
단동위원소 질량
115.06332853

개요

structure in first source

이름 및 식별자

우선 이름
N-Formylmorpholine
IUPAC
morpholine-4-carbaldehyde
현지명
4-포르밀모폴린
영어명
4-Formylmorpholine
분자식
C5H9NO2
분자량
115.13

이름 및 동의어

4-Formylmorpholine4394-85-84-MorpholinecarboxaldehydeN-FORMYLMORPHOLINEMorpholine, 4-formyl-DTXSID7044427D1E63XO4RHNSC-14833DTXCID5024427RefChem:99981224-518-3morpholine-4-carbaldehyde
이름 더 보기
4-포르밀모폴린N-포르밀모르폴린FormmorpholimeN-FormylmorpholN-Formyl MorpholinTIMTEC-BB SBB0076704-Formylmorpholine>
N-FormylmorfolinMFCD000061704-MorpholinecarbaldehydeN-formyl morpholineN-Formylmorfolin [Czech]formyl morpholineUNII-D1E63XO4RHN-formyhnorpholine

데이터베이스 식별자

CAS
4394-85-8
PubChem CID
20417
DTXSID
DTXSID7044427
UNII
D1E63XO4RH
EC Number
224-518-3
Nikkaji
J149.689A

물성

구조 계산 물성

XLogP
-0.6
극성 표면적
29.5 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
2
회전 가능 결합 수
0
무거운 원자 수
8

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Morpholines
SpringerMaterials PropertiesBoiling point
Vapor Pressure0.32 [mmHg]
Physical Description · 2건

Liquid; CBI

Clear colorless liquid; mp = 20-23 deg C; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점
20 · 20-23 °C (lit.)
끓는 점
236 · 236-237 °C (lit.)
밀도
1.145 g/mL · 1.145 g/mL at 25 °C (lit.)
증기압
0.03 hPa · 0.03 hPa (20 °C)
굴절률
20 · n20/D 1.485(lit.)
인화점
230 °F · >230 °F
화학적 성질 · 1건

CLEAR YELLOW LIQUIDN-formylmorpholine is a colourless transparent liquid soluble in water. It is chemically stable, non-toxic, and non-corrosive but can also dissolve aliphatic hydrocarbons, aromatic hydrocarbons, and water because of its unique structure. N-formylmorpholine would largely reduce the volatility of aromatic hydrocarbon when dissolving the latter. Thus, it can extract, distill and recycle aromatic hydrocarbon. Besides, this compound is also applied in C4 (LNG) cracking projects for desulfuration and solvent extraction, which can increase the yield (relative to DMF, ACN, and NMP processes). At present, this application has been adopted in China. It should be stored in sealed containers in a cool, ventilated warehouse. Keep away from fire and heat. Avoid the use of mechanical equipment that would produce sparks. Handle gently, avoiding damage to the packaging and containers.

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H317 (74.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P261, P264+P265, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 259 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

유해성 정보

Regulatory Information · 5건

Chemical: 4-Morpholinecarboxaldehyde

4-Morpholinecarboxaldehyde is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 4-Morpholinecarboxaldehyde are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 29-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/11158

4-Morpholinecarboxaldehyde: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1건

A mild skin and eye irritant; Oral LD50 (rat) = 6.5 mL/kg; [RTECS] May cause skin sensitization; [ECHA REACH Registrations] Search for (4394-85-8[EC/RN Number]) AND (dermatitis OR allergic OR sensitizer OR sensitization): no results; [PubMed] An eye and mild skin irritant; [Sigma-Aldrich MSDS]

Hazard Classes and Categories · 2건

Skin Sens. 1 (74.1%)

Skin sensitization - Category 1B

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
QD9694000
독성
LD50 orally in Rabbit: > 7360 mg/kg LD50 dermal Rabbit > 18400 mg/kg
HS 번호
29349990
risk_code
36/37/38

화학 및 산업

용도 및 제조

Uses · 2건

Used as an intermediate, laboratory reagent, in gas treatment, cleaning agents, and professional and consumer coatings; [ECHA REACH Registrations]

Painting (Pigments, Binders, and Biocides) [Category: Paint]

U.S. Production2023: 75,000 - <500,000 lb
Consumer UsesViscosity modifiers
Industry UsesIntermediate
General Manufacturing Information · 2건

Computer and Electronic Product Manufacturing

4-Morpholinecarboxaldehyde: ACTIVE

응용 분야 · 3건

개요4-Formylmorpholine is an excellent non-protonic solvent. It is widely used as a solvent and extractant for aromatics. It is used as a detergent for acid gases. In the field of organic synthesis, it can be used to prepare labelled 14C, 4-(trifluoromethyl)morpholine, 3-alkyl-2-chloro-5,6-dihydrobenzaldehyde, triple-biphenyldialdehyde and phenylpropargyl aldehyde. It plays an important role in the desulphurisation of natural gas, syngas, flue gas and petrol.

용도4-Formylmorpholine is widely used as a solvent and extracting agent for aromatics. It is used as a scrubbing agent for acidic gases. It is employed in the preparation of adenine hydrochloride labeled with 14C, 4-(trifluoromethyl)morpholine, 3-alkyl-2-chloro-5,6-dihydrobenzaldehyde and terphenyl dialdehyde. It plays an important role in the desulfurization of natural gas, synthetic gas, flue gas and gasoline.

일반 설명Treatment of 4-formylmorpholine with sulphur tetrafluoride in the presence of potassium fluoride gives 4-(trifluoromethyl)morpholine in excellent yields. 4-Formylmorpholine reacts with series of 2-alkyl-2-cyclohexen-1-ones in the presence of POCl3 to give the corresponding 3-alkyl-2-chloro-5,6-dihydrobenzaldehydes and allylic alcohols (by-product).

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
山东前元高分子材料有限公司18678041314 18765609661 · [email protected]
韶远科技(上海)有限公司021-50795510 4000665055 · [email protected]

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174건

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