5-Amino-2-methylpyridine (HCID 243313)

이름 및 식별자

우선 이름: 5-Amino-2-methylpyridine
IUPAC: 6-methylpyridin-3-amine
영어명: 5-Amino-2-methylpyridine
분자식: C6H8N2
분자량: 108.14

이름 및 동의어

5-Amino-2-methylpyridine6-methylpyridin-3-amine3430-14-6DTXSID00287854RefChem:532218DTXCID10239001625-232-53-Amino-6-methylpyridine5-Amino-2-picoline3-Amino-6-picoline6-methyl-3-pyridinamine80287-53-2

이름 더 보기

6-METHYL-PYRIDIN-3-YLAMINEAURORA KA-79235-Aminopicoline5-Amino-2-methylpyri6-Methyl-Pyridin-3-yl5-Amino-2-methypyridine

MFCD008333896-methylpyridine-3-amine5-amino-2-methylpyridin3-amino-6-methyl-pyridineNSC 52872PB32227PS-9287EN300-42380

데이터베이스 식별자

CAS: 3430-14-6
PubChem CID: 243313
DTXSID: DTXSID00287854
EC Number: 625-232-5
Nikkaji: J83.254E

물성

구조 계산 물성

XLogP: 0.5
극성 표면적: 38.9 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 8
형식 전하: 0
복잡도: 72.9

물리화학적 성질

녹는점: 95 · 95-99°C
끓는 점: 238.4 · 238.4±20.0 °C(Predicted)
밀도: 1.068 · 1.068±0.06 g/cm3(Predicted)
저장 조건: Keep in dark place,Inert atmosphere,Room temperature
산도 계수 (pKa): 6.89 · 6.89±0.10(Predicted)
물리적 상태: 가루
색상: 황백색에서 주황색, 갈색까지
InChI: InChI=1S/C6H8N2/c1-5-2-3-6(7)4-8-5/h2-4H,7H2,1H3
InChIKey: UENBBJXGCWILBM-UHFFFAOYSA-N
SMILES: C1=NC(C)=CC=C1N
LogP: 0.704 · 0.704

화학적 성질

White to orange to brown solid

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H301 (12.5%): Toxic if swallowed [Danger Acute toxicity, oral]

P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 48 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationStatus: Active Update: 07-06-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/29319

Hazard Classes and CategoriesAcute Tox. 3 (12.5%)

안전 데이터

wgk: 3
ridadr: UN2811
HS 번호: 29333999
risk_code: 22-37/38-41-36/37/38-34-24/25
hazard_code: Xn,Xi,C
safety_code: 26-36/39-45-36/37/39-36-27-36/37
포장분류: III
위험 등급: 6.1
위험 참고 사항: Harmful
Hazard Classifications: Acute Tox. 4 OralEye Dam. 1Skin Irrit. 2STOT SE 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야 · 2건

용도6-Methylpyridine-3-amine, is a heterocyclic building block used in the manufacture of various pharmaceutical compounds. It can be used for the synthesis of 2-aminoquinazoline derivatives, as a novel class of metabotropic glutamate receptor 5 negative allosteric modulators (mGluR5), leading toward a drug candidate for the treatment of l-DOPA induced dyskinesia.

일반 설명5-Amino-2-methylpyridine is used as a pharmaceutical intermediate for Omecamtiv Mecarbil, a selective cardiac myosin activator used to improve cardiac function.

상·하류 제품 정보

상류 원료

하류 제품

5-Methoxypyridine-2-carboxylic acid 6-Iodo-5-methoxy-2-pyridinecarboxylic acid 디에틸[[(6-메틸-2-피리딜)아미노]메틸렌]말로네이트 날리딕스산 에틸4-히드록시-7-메틸-1,8-나프티리딘-3-카르복실레이트 2-Iodo-3-methoxy-6-methylpyridine 4-히드록시-7-메틸-1,8-나프티리딘-3-카르복실산 2-Amino-5-hydroxypyridine 3-Hydroxy-2-iodo-6-methylpyridine 5-히드록시-2-메틸피리딘 5-Hydroxypyridine-2-carbohydrazide 5-Chloropyridine-2-carboxylic acid

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海泰矶林实业有限公司02150630626 17717886015 · [email protected]

연결된 노트

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5-Amino-2-methylpyridine

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