Ammonium dihydrogen phosphate

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

Residues of monoammonium phosphate are exempted from the requirement of a tolerance when used in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. Use: Postharvest fumigation in formulation with aluminum phosphide. Limit: No more than 3.75% by weight in formulation.

17 [mg/m3]

190 [mg/m3]

1100 [mg/m3]

/SIGNS AND SYMPTOMS/ Acute ... eye contact with concentrated alkali causes conjunctival edema and corneal destruction. Alkalies penetrate skin slowly. Extent of damage therefore depends on duration of contact. Chronic poisoning (from skin contact). Chronic dermatitis may follow repeated contact ... /Alkalies and Phosphates/

/OTHER TOXICITY INFORMATION/ ... With large doses of ... ammonium /salts/, there arises the possibility of sufficient absorption to produce diuresis and systemic ammonia poisoning, particularly if material is administered parenterally. /Ammonium Salts/

/LABORATORY ANIMALS: Acute Exposure/... It has been shown that solutions containing 0.1 molar ... ammonium phosphate ... at pH 7-7.5 made up to 0.46 osmolar (1.5 times isotonic concentration) by addition of sodium chloride or sucrose and dripped continuously on eyes of rabbits caused edema of epithelium of the cornea within 3-3.5 hr. /Ammonium Phosphate/

According to the 2006 TSCA Inventory Update Reporting data, the number of persons reasonably likely to be exposed in the industrial manufacturing, processing, and use of ammonium dihydrogen phosphate is 1000 or greater; the data may be greatly underestimated(1).

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Ammonia and related compounds/

/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for signs of pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mg/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize. /Ammonia and related compounds/

/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ammonium and related compounds/

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Phosphorus and related compounds/

For more Antidote and Emergency Treatment (Complete) data for AMMONIUM DIHYDROGEN PHOSPHATE (6 total), please visit the HSDB record page.

48.6

PPRTV Archive

0.09

PPRTV Current

FAO/WHO Expert Committee on Food Additives ... recommended ... /levels/ for total dietary phosphorus ... unconditional acceptance level /of less than 30 mg/kg body wt/ is considered safe in any type of diet ... conditional acceptance level /of 30-70 mg/kg body wt/ is acceptable only when dietary calcium level is high. /Phosphates/

LD50 Rabbit dermal >7940 mg/kg bw

LD50 Rat oral 5750 mg/kg bw

Monoammonium phosphate

9 x 10^-2 mg/kg-day

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Inadequate information to assess carcinogenic potential

2021

Substance added directly to human food affirmed as generally recognized as safe (GRAS).

Ammonium phosphate (mono-, and dibasic) used as a general purpose food additive in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Residues of monoammonium phosphate are exempted from the requirement of a tolerance when used in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. Use: Postharvest fumigation in formulation with aluminum phosphide. Limit: No more than 3.75% by weight in formulation.