Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
헥사나트륨 헥사메타인산염
마이크로메트(MICROMET)나트륨메타인산염(SODIUMMETAPHOSPHATE)인산나트륨 · 메타인산,헥사나트륨염(METAPHOSPHORICACID,HEXASODIUMSALT)헥사나트륨헥사메타인산염(HEXASODIUMHEXAMETAPHOSPHATE)헥사나트륨메타인산염(HEXASODIUMMETAPHOSPHATE)메디칼곤 · 육메타인산나트륨 · 헥사나트륨헥사메타인산염 · 육메타인산나트륨(SODIUMHEXAMETAPHOSPHATE) · 헥사메타인산나트륨 · 소듐헥사메타포스페이트 · SHMP
식별자 및 물리적 특성
| CAS No. | 10124-56-8 |
|---|---|
| 분자식 | Na6O18P6 |
| 평균 분자량 | 611.77 g/mol |
| 단동위원소 질량 | 611.68964862 g/mol |
| SMILES | O=P1([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])O1.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+] |
| InChIKey | GCLGEJMYGQKIIW-UHFFFAOYSA-H |
| PubChem CID | 24968 |
| EC No. | 688-275-9 |
| DTXSID | DTXSID1047522 |
| 현지명 | 헥사나트륨 헥사메타인산염 |
화학 및 물리적 성질
| 극성 표면적 | 296 |
|---|---|
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 18 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 30 |
| 형식 전하 | 0 |
| 복잡도 | 513 |
| 물질 분류 | Metals -> Phosphates, Metallic Salts |
| 화장품 | Cosmetic ingredients (Sodium Hexametaphosphate) -> CIR (Cosmetic Ingredient Review)Chelating |
| 식품 첨가물 | FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food |
| 용해도 | CLEAR, HYGROSCOPIC GLASSMP 628 °CSOL IN WATER, BUT DISSOLVES SLOWLYDEPOLYMERIZES IN AQ SOLN TO FORM SODIUM TRIMETAPHOSPHATE & SODIUM ORTHOPHOSPHATES. /POLYMERIC SODIUM METAPHOSPHATES/INSOL IN ORG SOLVENTS. /SODIUM HEXAMETAPHOSPHATE DETERGENTS/ |
| Animal Drugs | Pharmaceuticals -> UK Veterinary Medicines Directorate List |
| Decomposition | When heated to decomposition it emits toxic fumes of phosphoxides and Na2O.WHEN HEATED TO DECOMP, CAN EMIT HIGHLY TOXIC FUMES OF PO(X). |
| Physical Description | Polymeric sodium metaphosphates: Clear hygroscopic solidSoluble in water[HSDB] White odorless granules[MSDSonline] |
| Other Experimental Properties | It possesses sequestering, dispersing, and flocculating properties and precipitates proteins. In very low concentrations, it inhibits corrosion in steel and prevents the precipitation of slightly soluble, scale-forming compounds such as calcium carbonate and calcium sulfate. /Calgon/Depolymerizes in aqueous soln to form sodium trimetaphosphate and sodium orthophosphates.Miscible in water, but insoluble in organic solvents. /Calgon/ |
| 녹는점 | 616℃ |
| 끓는 점 | 1500℃ |
| 밀도 | 2.181 |
| 굴절률 | 1.482 |
| FEMA | 3027 | SODIUM HEXAMETAPHOSPHATE |
| 저장 조건 | 2-8°C |
| 물리적 상태 | 고체 |
| 색상 | 하얀색 |
| 냄새 | 냄새 없는 |
| 용해도 | 물에 용해됩니다. 유기 용매에 불용성 |
| 안정성 | 안정적인. 건조한 상태로 유지하세요. |
| 화장품 원료 기능 | 킬레이팅부식 방지향기 |
| InChI | 1S/6Na.H6O18P6/c1-19(2)13-20(3,4)15-22(7,8)17-24(11,12)18-23(9,10)16-21(5,6)14-19/h(H,1,2)(H,3,4)(H,5,6)(H,7,8)(H,9,10)(H,11,12)/q6*+1/p-6 |
| InChIKey | INSNVPUOJJTBAL-UHFFFAOYSA-H |
| SMILES | [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[P]1(=O)(O[P](=O)(O[P](=O)(O[P](=O)(O[P](=O)(O[P](=O)(O1)[O-])[O-])[O-])[O-])[O-])[O-] |
| EPA | Sodium hexametaphosphate (10124-56-8) |
화학적 성질
The sodium polyphosphates class consists of several amorphous, water soluble polyphosphates composed of linear chains of metaphosphate units, (NaPO3)x where x ≥ 2, terminated by Na2PO4- groups. They are usually identified by their Na2O/ P2O5 ratio or their P2O5 content. The Na2O/P2O5 ratios vary from about 1.3 for sodium tetrapolyphosphate, where x = approximately 4; through about 1.1 for Graham’s salt, commonly called sodium hexametaphosphate, where x = 13 to 18; to about 1.0 for the higher molecular weight sodium polyphosphates, where x = 20 to 100 or more. The pH of their solution varies from about 3 to 9. For additional details of description, refer to Burdock (1997).
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 100% (19 of 19) of all reports.Not ClassifiedAggregated GHS information provided per 19 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| 규제 정보 | Chemical: Metaphosphoric acid (H6P6O18), hexasodium saltSodium hexametaphosphate: Does not have an individual approval but may be used under an appropriate group standard |
| 유해성 요약 | Emergency treatment: IrritantsCaused severe kidney damage in rats fed 3% and 5%, while 1.8% caused no damage[HSDB] An irritant[MSDSonline] |
| FDA 요건 | Sodium hexametaphosphate used as a sequestrant in food for human consumption is generally recognized as safe when used in accordance with good manufacturing practice.Sodium hexametaphosphate used as a sequestrant in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice. |
| FIFRA 요건 | Residues of sodium hexametaphosphate are exempted from the requirement of a tolerance when used as a surfactant, emulsifier, wetting agent, suspending agent, dispersing agent or buffer in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. |
| CERCLA 보고 수량 | Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 2270 kg. The toll free number of the NRC is (800) 424-8802In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b). |
| Hazard Classes and Categories | Not Classified |
| Skin, Eye, and Respiratory Irritations | EYE CONTACT WITH CONCENTRATED ALKALI CAUSES CONJUNCTIVAL EDEMA & CORNEAL DESTRUCTION. A. ALKALIES PENETRATE SKIN SLOWLY. EXTENT OF DAMAGE THEREFORE DEPENDS ON DURATION OF CONTACT. B. CHRONIC POISONING (FROM SKIN CONTACT). CHRONIC DERMATITIS MAY FOLLOW REPEATED CONTACT ... . /ALKALIES/ |
| Firefighting Hazards | Behavior in fire: May melt with loss of steam. /Sodium Phosphates/ |
| 처리 방법 | SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices. |
| Allowable Tolerances | Residues of sodium hexametaphosphate are exempted from the requirement of a tolerance when used as a surfactant, emulsifier, wetting agent, suspending agent, dispersing agent or buffer in accordance with good agricultural practices as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest. |
| Personal Protective Equipment (PPE) | Respiratory protection (supplied-air respirator with full facepiece or self-contained breathing apparatus) should be available where these compounds are manufactured or used and should be worn in case of emergency and overexposure. /Phosphorus compounds/ |
| 독성 요약 | The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Sodium Hexametaphosphate...Safe for use in cosmetics, with qualifications |
| Human Toxicity Excerpts | ... /0.1% & 5% SOLN OF CALGON/ WERE FOUND MUCH TOO INJURIOUS TO USE FOR THE PURPOSE OF REMOVING CALCIUM FROM THE CORNEA. /CALGON/NO HEALTH HAZARDS ARE ASSOCIATED WITH SODIUM HEXAMETAPHOSPHATE IN FOODS & NATURAL WATERS.... /SODIUM/ SALTS, SUCH AS METAPHOSPHATES, ARE TOXIC PROBABLY BECAUSE OF THEIR EXCESS ALKALINITY RATHER THAN FROM SIMPLE SODIUM EXCESS. /SODIUM METAPHOSPHATES/ACUTE POISONING BY INJESTION: ... EVEN THOUGH PATIENTS RECOVER FROM IMMEDIATE DAMAGE, ESOPHAGEAL STRICTURE CAN OCCUR WK, MO, OR YR LATER TO MAKE SWALLOWING DIFFICULT. INGESTION OF TRIPOLYPHOSPHATE ... IN ... DETERGENTS OR LAXATIVES CAUSE SHOCK-LIKE STATE, FALL OF BLOOD PRESSURE, SLOW PULSE, CYANOSIS COMA & SOMETIMES TETANY AS RESULT OF REDN IN IONIC CALCIUM. /ALKALIES/For more Human Toxicity Excerpts (Complete) data for SODIUM HEXAMETAPHOSPHATE (7 total), please visit the HSDB record page. |
| Environmental Bioconcentration | A comprehensive examination of metal levels at various trophic levels within an undisturbed Precambrian Shield lake ecosystem was made. Concn of 21 naturally occurring elements including phosphorus were measured in sediments, clams, fish, birds, and mammals. Mercury was the only element to exhibit biomagnification. /Phosphorus/ |
| Non-Human Toxicity Excerpts | ... FEEDING RATS 3% & 5% ... SODIUM HEXAMETAPHOSPHATE RESULTED IN SEVERE KIDNEY DAMAGE, WHILE FEEDING 1.8% ... CAUSED NO OBSERVABLE PHYSIOLOGICAL DAMAGE. ... HOWEVER, WHEN DOGS WERE FED INCREASING DOSAGES ... BEGINNING AT 1.0 G/KG/DAY AND INCREASING TO 4.0 G/KG FOR THE LAST MONTH OF A 5-MONTH FEEDING PERIOD, THE DOGS ... BEGAN TO LOSE WEIGHT WHEN THE DAILY DOSE REACHED 2.5 G/KG/DAY.SODIUM HEXAMETAPHOSPHATE DID NOT EXHIBIT GENETIC ACTIVITY IN THE FOLLOWING IN VITRO MICROBIAL ASSAYS: S TYPHIMURIUM (PLATE TESTS, NON-ACTIVATION SUSPENSION TESTS, ACTIVATION SUSPENSION TESTS)S CEREVISIAE (NON-ACTIVATION & ACTIVATION SUSPENSION TESTS).ORAL ADMIN OF UP TO 240 MG/KG BODY WT TO PREGNANT RATS & UP TO 370 MG/KG BODY WT TO PREGNANT MICE (BOTH FOR 10 CONSECUTIVE DAYS) HAD NO DISCERNIBLE EFFECT ON NIDATION OR ON MATERNAL OR FETAL SURVIVAL. SOFT & SKELETAL TISSUE ABNORMALITIES SAME AS CONTROL.Studies of animals showed that ... sodium hexametaphosphate fed at high concentrations in water /interferes/ ... with trace metal metabolism.Sodium hexametaphosphate depressed the growth of 7 strains of Streptococcus mutans (serotype a-g) as assessed by disk diffusion methods. Minimal inhibitory concn of condensed phosphates on growth of strain Kl-R (g) in a chemically defined medium were measured turbidimetrically. The minimal inhibitory concn of condensed phosphates on Streptococcus mutans appeared to be related to their chelating capacity. As the growth inhibition by condensed phosphates was reversed by the addition of divalent metal ions (calcium(2+), magnesium(2+), manganese(2+)), the chelating capacity of condensed phosphates was apparently responsible for their antibacterial action. |
| RAIS Toxicity Values | 1PPRTV Current4 |
| Non-Human Toxicity Values | LD50 Rat oral 6200 mg/kgLD50 Mouse oral 4320 mg/kgLD50 Mouse ip 870 mg/kgLD50 Mouse sc 1300 mg/kgLD50 Mouse iv 62 mg/kg |
| Hazard Quotient Level 0.1 or Cancer Risk Level 1E-06 | 7.80e+041.20e+062.00e+041.5E+01(G)1.00e+00Volatile |
| Hazard Quotient Level 3 or Cancer Risk Level 1E-04 | 2.30e+053.50e+066.00e+041.5E+01 (G)1.00e+00Volatile |
| 수질 위해 등급(WGK) | WGK 1 slightly water endangering |
| TSCA 등재 상태 | TSCA listed |
| 관세 코드 | 2835390000 |
| 안전 문구(S) | 24/25 |
| 기존화학 물질 | KE-19835 |
| 저장 분류 | 11 - Combustible Solids |
| 유해 물질 데이터 | 10124-56-8(Hazardous Substances Data) |
용도
용도
1. 금 속이온 봉쇄작용, 완충작용, 분산작용, 세척작용 2. 수처리, 제지, 염 색조제, 금속표면처리, 방 첨 제 3. 육류의 결착성을 향상시키므로 햄, 소시지 어륙반죽 제품에 0.3% 용된 다. 4. 간장, 된 장 의 변색방지, 점조성부여등의 목적으로 0.01~0.2%첨가. 5. 물엿의 변색, 착색방지, 주류 청량 음 료 등의 침전방지에도 효과가 있으며 밀국수, 메밀국수, 기타 면의 감촉을 좋게하고 수산물 건제품 의 지방산화를 억제하 며, 광택유지에 효과가 있다. 6. 게, 연어, 송어, 다랑어등의 통조림에 생 성 되는 struvite방지
용도
sodium hexametaphosphate is a chelating agent and a corrosion inhibitor. This is an inorganic salt.
제조 및 합성 방법
제조 방법
Sodium hexametaphosphate is prepared by heating monosodium phosphate (NaH2PO4) rapidly to a clear melt, which occurs slightly above 625°C. Rapid chilling of this melt produces a very soluble glass, which is then crushed or milled.