CAS 13435-12-6 Acetamide, N-(trimethylsilyl)- (HCID 25989)

이름 및 식별자

우선 이름: Acetamide, N-(trimethylsilyl)-
IUPAC: N-trimethylsilylacetamide
영어명: N-(Trimethylsilyl)acetamide
분자식: C5H13NOSi
분자량: 131.25

이름 및 동의어

N-(Trimethylsilyl)acetamide13435-12-6N-TrimethylsilylacetamideACETAMIDE, N-(TRIMETHYLSILYL)-Trimethylsilylacetamide(Acetylamino)trimethylsilaneEINECS 236-565-7NSC 139859BRN 0741928DTXSID80654544-04-00-04011 (Beilstein Handbook Reference)RefChem:551795

이름 더 보기

trimethylsilylTMSACMH3DK063CMD1YLVNC9C15orf13HEL-S-265HTM-alpha

DTXCID2034205236-565-7C5H13NOSiAcetamide, TMS derivativeMFCD00008671n-trimethylsilyl-acetamideTMS acetamideS18875

데이터베이스 식별자

CAS: 13435-12-6
PubChem CID: 25989
DTXSID: DTXSID8065454
EC Number: 236-565-7
Nikkaji: J55.333F

물성

구조 계산 물성

극성 표면적: 29.1 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 1
회전 가능 결합 수: 1
무거운 원자 수: 8
형식 전하: 0
복잡도: 95

물리화학적 성질

녹는점: 46 · 46-49 °C(lit.)
끓는 점: 84 °C18 · 84 °C18 mm Hg(lit.)
밀도: 0.859 · 0.859±0.06 g/cm3(Predicted)
인화점: 135 °F · 135 °F
저장 조건: Inert atmosphere,Room Temperature
용해도: 클로로포름, DMSO, 메탄올 에 용해됨
산도 계수 (pKa): 18.23 · 18.23±0.46(Predicted)
물리적 상태: 결정질 덩어리
색상: 흰색에서 노란색으로
수용성: 물과 반응
BRN: 741928 · 741928
안정성: 수분에 민감한
InChI: 1S/C5H13NOSi/c1-5(7)6-8(2,3)4/h1-4H3,(H,6,7)
InChIKey: LWFWUJCJKPUZLV-UHFFFAOYSA-N
SMILES: CC(=O)N[Si](C)(C)C
EPA: Acetamide, N-(trimethylsilyl)- (13435-12-6)

화학적 성질

WHITE TO YELLOWISH CRYSTALLINE MASS

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 84.4% (38 of 45) of all reports.

Warning

H315 (11.1%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (11.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 38 of 45 reports by companies.；There are 4 notifications provided by 7 of 45 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Chemical: Acetamide, N-(trimethylsilyl)-

Acetamide, N-(trimethylsilyl)-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (11.1%)；Eye Irrit. 2 (11.1%)

규제 정보

Regulatory Information · 2건

Chemical: Acetamide, N-(trimethylsilyl)-

Acetamide, N-(trimethylsilyl)-: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: AD0250000
ridadr: 1325
HS 번호: 29319090
risk_code: 36/37/38-11
hazard_code: Xi-F,Xi,F
safety_code: 37/39-26
포장분류: III
위험 등급: 4.1
F 고인화성물질: 10-21
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

General Manufacturing InformationAcetamide, N-(trimethylsilyl)-: ACTIVE

응용 분야

용도N-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).

일반 설명The efficiency of N-(Trimethylsilyl)acetamide (TMS acetamide) as allyl group scavenger and its compatibility with Fluorenylmethyloxycarbonyl chloride (Fmoc) protecting groups were studied.