2- (트리메틸 실릴)에 톡시 메틸 클로라이드

2-Chloromethyl 2-(trimethylsilyl)ethyl ether

HCID 2724271CAS 76513-69-4

부분 구조 검색 유사 구조 찾기

기본 정보

표준 SMILES: C[Si](C)(C)CCOCCl
InChIKey: BPXKZEMBEZGUAH-UHFFFAOYSA-N
분자식: C6H15ClOSi
평균 분자량: 166.72 g/mol
단동위원소 질량: 166.05806931

이름 및 식별자

우선 이름: 2-Chloromethyl 2-(trimethylsilyl)ethyl ether
IUPAC: 2-(chloromethoxy)ethyl-trimethylsilane
현지명: 2- (트리메틸 실릴)에 톡시 메틸 클로라이드
영어명: 2-(Trimethylsilyl)ethoxymethyl chloride
분자식: C6H15ClOSi
분자량: 166.72

이름 및 동의어

76513-69-42-(Trimethylsilyl)ethoxymethyl chloride2-Chloromethyl 2-(trimethylsilyl)ethyl etherSILANE, [2-(CHLOROMETHOXY)ETHYL]TRIMETHYL-EINECS 278-483-4DTXSID10227327Silane, (2-(chloromethoxy)ethyl)trimethyl-RefChem:470470DTXCID10149818Silane, 2-(chloromethoxy)ethyltrimethyl-278-483-4(2-(CHLOROMETHOXY)ETHYL)TRIMETHYLSILANE

이름 더 보기

2-(트리메틸실릴)에톡시메틸클로라이드SEM-CI(2-trimethylethylsilylethoxy)methyl chloride2-(CHLOROMETHOXY)ETHYLTRIMETHYLSILANE(Trimethylsilyl)ethoxymethyl chloride{2-[(chloromethyl)oxy]ethyl}(trimethyl)silaneDK8912-(Trime

SEM-chloride2-(Trimethylsilyl)ethoxymethylchlorideSEM-Cl[2-(chloromethoxy)ethyl]trimethylsilane2-(chloromethoxy)ethyl-trimethylsilaneMFCD00009919C6H15ClOSiSEM chloride

데이터베이스 식별자

CAS: 76513-69-4
PubChem CID: 2724271
DTXSID: DTXSID10227327
UNII: G8Q8Y64LT8
EC Number: 278-483-4
Nikkaji: J319.335G

물성

구조 계산 물성

극성 표면적: 9.2 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 1
회전 가능 결합 수: 4
무거운 원자 수: 9
형식 전하: 0
복잡도: 69.9

물리화학적 성질

끓는 점: 170 · 170-172 °C (lit.) 57-59 °C/8 mmHg (lit.)
밀도: 0.942 g/mL · 0.942 g/mL at 25 °C (lit.)
굴절률: 20 · n20/D 1.435(lit.)
인화점: 116 °F · 116 °F
저장 조건: 2 · 2-8°C
용해도: Sol most organic solvents (pentane, CH2Cl2, Et2O, THF, DMF, DMPU, HMPA)
물리적 상태: 액체
색상: 무색의
Specific Gravity: 0.95 · 0.95
수용성: 물에서 분해되다
BRN: 3587289 · 3587289
안정성: 솔루션이 불안정함
InChI: 1S/C6H15ClOSi/c1-9(2,3)5-4-8-6-7/h4-6H2,1-3H3
InChIKey: BPXKZEMBEZGUAH-UHFFFAOYSA-N
SMILES: C[Si](C)(C)CCOCCl

화학적 성질

Colorless to light yellow liqui

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 27-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/34974

Silane, 2-(chloromethoxy)ethyltrimethyl-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesFlam. Liq. 3 (100%)

안전 데이터

wgk: 3
tsca: No
ridadr: UN 2920 8/PG 2
HS 번호: 29319090
risk_code: 10-34
hazard_code: C
safety_code: 26-28-36/37/39-45-16
포장분류: III
위험 등급: 3.2
F 고인화성물질: 8-10-21
Hazard Classifications: Flam. Liq. 3Skin Corr. 1B
스토리지 클래스: 3 - Flammable liquids

화학 및 산업

응용 분야 · 2건

용도2-(Trimethylsilyl)ethoxymethyl Chloride is a reagent used in the protection of alcohols, secondary aryl amines, and imidazole, indole, and pyrrole nitrogens;electrophilic formaldehyde equivalent; acyl anion equivalent,used in One-carbon Homologations, Cyclizations etc.

일반 설명2-(Trimethylsilyl)ethoxymethyl chloride (SEM-Cl) is a widely used reagent for the preparation protection groups for amines, alcohols, phenols, and carboxy groups. The nitrogen of amides and sulfonamides groups are also protected by using SEM-Cl reagent.