스테아린산 나트륨

Sodium Stearate

HCID 2724691

기본 정보

CAS
822-16-2
표준 SMILES
CCCCCCCCCCCCCCCCCC(=O)[O-].[Na+]
InChIKey
RYYKJJJTJZKILX-UHFFFAOYSA-M
분자식
C18H35NaO2
평균 분자량
306.5 g/mol
단동위원소 질량
306.25347464

이름 및 식별자

우선 이름
Sodium Stearate
IUPAC
sodium octadecanoate
현지명
스테아린산 나트륨
영어명
Sodium stearate
분자식
C18H35NaO2
분자량
306.45907

이름 및 동의어

SODIUM STEARATE822-16-2Sodium octadecanoateOctadecanoic acid, sodium saltFlexichem BStearic acid, sodium saltProdhygineBonderlube 235Edenor FHTINonsoul sn 15QU7E2XA9TGRhenogran nast 50acmf-ge1858
이름 더 보기
나트륨옥타데카노산옥타데카노산,나트륨염스테아르산,나트륨염스테아린산나트륨나트륨스테아르산옥타데카노산,나트륨플렉시켐B본데를루베235프로드히긴나트륨옥소듐스테아레이트스테아린산나트륨스테아르산 나트륨스테아르산 나트륨염옥타데카노에이트 나트륨NatriumstearatSodiuM stearatOCTADECANOIC ACID SODIUM SALTflexichembbonderlube235stearatedesodiumSodiumStearate>Stearate (sodium)
Prifer 1634E-470(I)STEARIC ACID, SODIUM SALTDTXSID9027318CHEBI:132109RefChem:6249DTXCID807318212-490-5sodium;octadecanoate

데이터베이스 식별자

CAS
822-16-2
PubChem CID
2724691
DTXSID
DTXSID9027318
ChEMBL
CHEMBL1906423
ChEBI
CHEBI:132109
UNII
QU7E2XA9TG
EC Number
212-490-5
Nikkaji
J7.124B

물성

구조 계산 물성

극성 표면적
40.1 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
2
회전 가능 결합 수
16
무거운 원자 수
21

실험 및 물리화학적 성질

pHAQ SOLN IS STRONGLY ALKALINE, DUE TO HYDROLYSIS; ALC SOLN IS PRACTICALLY NEUTRAL
OdorSLIGHT, TALLOW-LIKE ODOR
Color/FormWHITE POWDER
Solubility · 2건

SLOWLY SOL IN COLD WATER OR COLD ALC; FREELY SOL IN HOT SOLVENTS

INSOL IN MANY ORGANIC SOLVENTS

Physical Description · 3건

Liquid; Dry Powder; Large Crystals; Large Crystals; Dry Powder

White to yellow powder or wax-like substance; Stearates are salts of octadecanoic acid; [ACGIH]

White solid; [Merck Index] White powder; [MSDSonline]

Stability/Shelf LifeAFFECTED BY LIGHT

물리화학적 성질

녹는점
270 °C · 270 °C
밀도
1.07 g/cm3 · 1.07 g/cm3
저장 조건
2 · 2-8°C
용해도
물과 에탄올(96%)에 약간 용해됩니다.
물리적 상태
가루
색상
하얀색

화학적 성질

Sodium stearate, NaC18H35O2, white to off-white powder, soluble, froth or foam upon shaking the water solution (soap), formed by reaction of NaOH and stearic acid (in alcoholic solution) and evaporating. Used as a source of stearate.

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 75.6% (391 of 517) of all reports.

Danger

H315 (19.3%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (19%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P264, P264+P265, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 517 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 391 of 517 reports by companies.;There are 5 notifications provided by 126 of 517 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 3건

Chemical: Octadecanoic acid, sodium salt

Octadecanoic acid, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Sodium stearate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Octadecanoic acid, sodium salt: Human health tier I assessment;IMAP assessments - Octadecanoic acid, sodium salt: Environment tier I assessment
Hazards Summary · 2건

This TLV Documentation applies only to stearic acid and magnesium, sodium, and zinc stearates. It excludes stearates of other metals. TLV Basis is lower respiratory tract irritation. No acute systemic effects of stearic acid have been reported after ingestion. . . . Sprague-Dawley rats fed stearic acid in their diet at 3000 ppm for 209 days showed 'severe pulmonary infection consisting of tracheobronchitis, lobular pneumonia, lipoid histiocytic response, and abscess formation.' [ACGIH] See Stearic acid.

May cause irritation; [MSDSonline] See STEARATES.

Special Reports · 2건

THE CHEMICAL & PHYSICAL PROPERTIES (INCLUDING SOLUBILITY IN VARIOUS MEDIA) OF SODIUM STEARATE ARE REVIEWED.[LOWER ES; EXAMINATION OF SODIUM STEARATE SOAP; SOAP PERFUM COSMET 54(DEC) 659 (1981)]

THE EFFECT OF TEMPERATURE ON THE DENSITY & VISCOSITY OF SODIUM STEARATE IS DISCUSSED, ALONG WITH ITS LOW TOXICITY & USES IN A WIDE VARIETY OF FORMULATIONS INCLUDING COSMETICS, LUBRICANTS, POLYMERS & RUBBERS.[LOWER ES; SODIUM STEARATE. PART 2. USES; SOAP PERFUM COSMET 55(FEB) 85 (1982)]

EPA Safer ChemicalChemical: Sodium stearate; Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.
Hazard Classes and Categories · 3건

Skin Irrit. 2 (19.3%);Eye Dam. 1 (19%)

Serious eye damage/eye irritation - Category 2A;Hazardous to the aquatic environment (Acute) - Category 2;Hazardous to the aquatic environment (Long-term) - Category 2

Hazardous to the aquatic environment (Acute) - Category 2;Hazardous to the aquatic environment (Long-term) - Category 3

안전 및 보호

Threshold Limit Values (TLV) · 5건

10.0 [mg/m3], inhalable particulate matter (3 mg/m3 for respirable particulate matter)

10.0 [mg/m3], inhalable particulate matter (3 mg/m3 for respirable particulate matter)

8 hr Time Weighted Avg (TWA): 10 mg/cu m. /Stearates; does not include stearates of toxic metals/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Stearates; does not include stearates of toxic metals/

A4; Not classifiable as a human carcinogen. /Stearates; does not include stearates of toxic metals/

Protective Action Criteria (PAC) · 3건

0.17 [mg/m3]

1.8 [mg/m3]

11 [mg/m3]

독성 정보

Adverse Effects · 2건

ACGIH Carcinogen - Not Classifiable.

ACGIH Carcinogen - Not Classifiable.

Toxicity Summary · 2건

The CIR Expert Panel concluded that the following ingredients are safe in the present practices of use andconcentration described in the safety assessment when formulated to be non-irritating and non-sensitizing, which may be basedon a QRA...Sodium Stearate...

Safe for use in cosmetics, with qualifications

Human Toxicity Excerpts · 2건

SEE SOAPS. BY INTRAUTERINE INJECTION (AS IN SOME CRIMINAL ABORTIONS), SOAPS CAUSE HEMOLYSIS, EMBOLI, HYPERPYREXIA, SHOCK, RENAL DAMAGE, & OFTEN PROMPT DEATH. /SOAPS/

SEE SOAPS. THEY ARE...LESS LETHAL THAN SYNTHETIC ANIONIC DETERGENTS & EVEN LESS THAN MOST NONIONIC DETERGENTS. HOWEVER, SOAPS WITH APPRECIABLE CONTENT OF FREE ALKALI (EG, SOME LAUNDRY SOAPS) ARE LESS BENIGN. /SOAPS/

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
Non-Human Toxicity Excerpts · 4건

SEE SOAP. EXPERIMENTAL APPLICATION OF PURE GRANULATED WHITE SOAP TO RABBIT EYES CAUSES A MODERATELY SEVERE REACTION, GRADED 8 ON A SCALE OF 1 TO 10 AFTER 24 HR. ...SIMILARLY 5% SOLN OF SOAP CAUSES TRANSIENT MILD CONJUNCTIVAL HYPEREMIA & OPTICAL IRREGULARITY OF THE CORNEAL EPITHELIUM IF THE EXPOSURE IS BRIEF. /SOAP/

SODIUM STEARATE PRODUCED HYPERTHERMIA WHEN INJECTED INTO THE CEREBRAL VENTRICLES OF CONSCIOUS CATS. THRESHOLD EFFECTS WERE OBTAINED WITH AS LITTLE AS 2.0-5.0 MUG. THE HYPERTHERMIC EFFECT REACHED ITS MAXIMUM 2-3 HR AFTER ADMIN & LASTED FOR MORE THAN 12 HR. THE RISE IN TEMPERATURE WAS ALWAYS ASSOCIATED WITH SEDATION.

CULTURES OF RAT HEART MUSCLE (M) & ENDOTHELIOID (E) CELLS WERE TREATED FOR 30 MINUTES WITH SODIUM STEARATE AT CONCN OF 5X10-6 & 5X10-4 MOLAR & A FREE FATTY ACID (FFA)-TO-ALBUMIN RATIO OF 6:1. SODIUM STEARATE LABILIZED M CELL LYSOSOMES, BUT LYSOSOMES OF E CELLS WERE NOT SIGNIFICANTLY AFFECTED.

SODIUM STEARATE INDUCED PLASMA PLATELET AGGREGATION IN VITRO & THROMBOPENIA IN RABBITS AFTER INJECTION.

Evidence for CarcinogenicityA4; Not classifiable as a human carcinogen. /Stearates; does not include stearates of toxic metals/

규제 정보

Regulatory Information · 3건

Chemical: Octadecanoic acid, sodium salt

Octadecanoic acid, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Sodium stearate: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
WI4725000
ridadr
3077
HS 번호
29157090
safety_code
24/25

화학 및 산업

용도 및 제조

Uses · 6건

CIR ingredient: Sodium Stearate

Used in cosmetics, pharmaceuticals, food additives, waterproofing agents, plastic stabilizers, emulsifiers, and rubber lubricants and dusting agents; Stearic acid occurs naturally in human and animal fats and oils and in some vegetable oils, including cocoa oil. Stearic acid can be prepared from animal fat (triglyceride) by treating with water at high temperature, leading to hydrolysis of triglycerides, or by hydrogenation of unsaturated vegetable oils such as cottonseed oil. [ACGIH]

Used in pharmaceuticals (emulsifying and stiffening agent); in glycerol suppositories; in toothpastes; as waterproofing agent; as gelling agent; in cosmetics; as stabilizer in plastics; and as topical medication; [HSDB] Used in various cleaning products (most common ingredient in soap); as food additive (binder, emulsifier, and anti-caking agent); [CHEMINFO]

IN GLYCEROL SUPPOSITORIES; ALSO IN TOOTHPASTE; AS WATERPROOFING AGENT; PHARMACEUTIC AID (EMULSIFYING & STIFFENING AGENT)

MEDICATION: HAS BEEN USED TOPICALLY IN SYCOSIS & OTHER SKIN DISEASES

GELLING AGENT; IN COSMETICS; STABILIZER IN PLASTICS

ImpuritiesUSUALLY CONTAINS SODIUM PALMITATE
U.S. Exports(1986) No Data
U.S. Imports(1986) No Data
U.S. Production · 2건

2023: 5,500,000 - <7,000,000 lb;2022: 7,000,000 - <8,500,000 lb;2021: 7,000,000 - <8,500,000 lb;2020: 5,500,000 - <7,000,000 lb

(1986) No Data

Consumer UsesPolymerization promoter;Lubricating agent;Surfactant (surface active agent);Thickening agent;Emulsifier

응용 분야

개요Sodium stearate is the sodium salt of stearic acid. This white solid is the most common soap. It is found in many types of solid deodorants, rubbers, latex paints, and inks. It is also a component of some food additives and food flavorings.

용도sodium stearate is a fatty acid used as a waterproofing agent. Sodium stearate is one of the least allergy-causing sodium salts of fatty acids. It is non-irritating to the skin.

제조 방법 · 1건

생산 방법Sodium stearate is produced as a major component of soap upon saponification of oils and fats. The percentage of the sodium stearate depends on the ingredient fats. Tallow is especially high in stearic acid content (as the triglyceride), whereas most fats only contain a few percent. The idealized equation for the formation of sodium stearate from stearin (the triglyceride of stearic acid) follows : (C18H35O2)3C3H5 → C3H5(OH)3 + 3 C17H35CO2Na Purified sodium stearate can be made by neutralizing stearic acid with sodium hydroxide.

공급사100 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

추가 설명

정의ChEBI: Sodium octadecanoate is an organic sodium salt comprising equal numbers of sodium and stearate ions. It has a role as a detergent. It contains an octadecanoate.

관련 반응

33건

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