CAS 202982-70-5 3-Chloro-5-fluorophenol (HCID 2773713)

이름 및 식별자

우선 이름: 3-Chloro-5-fluorophenol
IUPAC: 3-chloro-5-fluorophenol
영어명: 3-Chloro-5-fluorophenol
분자식: C6H4ClFO
분자량: 146.55

이름 및 동의어

3-Chloro-5-fluorophenol202982-70-5DTXSID10378661RefChem:93462DTXCID60329688606-511-0Phenol, 3-chloro-5-fluoro-3-chloro-5-fluoro-phenolMFCD00042212SCHEMBL2218393-Chloro-5-fluorophenol, AldrichCPRAKOS006230029

이름 더 보기

3-Chloro-5-fluorophenol98%3-Chloro-5-fluorophenol 98%Phenol, 3-chloro-5-fluoro- (9CI)3-Chloro-4-fluoro-α,α,α-trifluorotoluene3-CHLORO-5-FLUOROPHENOL ISO 9001：2015 REACH

CS-W005519PS-8946AC-28533EN300-2483383-chloranyl-5-fluoranyl-phenolAM82862FT-0657199SCHEMBL9645386

데이터베이스 식별자

CAS: 202982-70-5
PubChem CID: 2773713
DTXSID: DTXSID10378661
EC Number: 606-511-0

물성

구조 계산 물성

XLogP: 3.1
극성 표면적: 20.2 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 9
형식 전하: 0
복잡도: 99

물리화학적 성질

끓는 점: 206 · 206.0±20.0 °C(Predicted)
밀도: 1.408 · 1.408±0.06 g/cm3(Predicted)
굴절률: 1.537 · 1.537
저장 조건: Inert atmosphere,Room Temperature
산도 계수 (pKa): 8.01 · 8.01±0.10(Predicted)
물리적 상태: 액체
색상: 투명한
수용성: 물과 섞이지 않습니다.

안전 및 규제

GHS 분류

GHS Classification · 5건

Danger

H302+H312 (11.1%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal]；H302 (66.7%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (66.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H314 (77.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H315 (22.2%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (22.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (22.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H411 (77.8%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 9 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesAcute Tox. 4 (66.7%)；Acute Tox. 4 (66.7%)；Skin Corr. 1B (77.8%)；Skin Irrit. 2 (22.2%)；Eye Irrit. 2 (22.2%)；STOT SE 3 (22.2%)；Aquatic Chronic 2 (77.8%)

안전 데이터

ridadr: UN3265
HS 번호: 2908190090
risk_code: 20/21/22-36/37/38-22
hazard_code: Xi,Xn
safety_code: 26-36/37/39
위험 등급: 8
위험 참고 사항: Irritant

화학 및 산업

응용 분야 · 1건

용도3-Chloro-5-fluorophenol is used as an intermediate in organic synthesis. It plays an important role in the preparation of substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor, substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.