CAS 7305-71-7 2-Amino-5-methylthiazole (HCID 351770)

개요

binds the W191G cavity of E coli cytochrome c peroxidase

이름 및 식별자

우선 이름: 2-Amino-5-methylthiazole
IUPAC: 5-methyl-1,3-thiazol-2-amine
영어명: 2-Amino-5-methylthiazole
분자식: C4H6N2S
분자량: 114.17

이름 및 동의어

2-Amino-5-methylthiazole7305-71-75-Methyl-1,3-thiazol-2-amine2-Thiazolamine, 5-methyl-2-Amino-5-methyl-thiazole5-Methyl-2-aminothiazole5-METHYL-2-THIAZOLAMINE(5-Methylthiazol-2-yl)amine7RAB78AF2PNSC-523150DTXSID102233292a5mt cpd

이름 더 보기

2,5-amthNSC 523150AKOS BBS-00006638BUTTPARK 18\10-87Meloxicam usp RC B2-Amino-5-methylthiaLABOTEST-BB LT000806452 mino-5-methylthiazole

RefChem:464648DTXCID60145820423-800-5615-902-55-methylthiazol-2-amineMeloxicam EP Impurity BMFCD00078317Thiazole, 2-amino-5-methyl-

데이터베이스 식별자

CAS: 7305-71-7
PubChem CID: 351770
DTXSID: DTXSID10223329
ChEMBL: CHEMBL502447
UNII: 7RAB78AF2P
EC Number: 423-800-5、615-902-5
Nikkaji: J382.938C

물성

구조 계산 물성

XLogP: 1
극성 표면적: 67.2 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 0
무거운 원자 수: 7
형식 전하: 0
복잡도: 66.7

물리화학적 성질

녹는점: 93 · 93-98 °C (lit.)
끓는 점: 232.5 · 232.5±9.0 °C(Predicted)
밀도: 1.258 · 1.258±0.06 g/cm3(Predicted)
증기압: 0.153 · 0.153-1.24Pa at 20-40℃
저장 조건: 2 · 2-8°C
용해도: 메탄올에 용해됨
산도 계수 (pKa): 5.42 · 5.42±0.10(Predicted)
물리적 상태: 가루
색상: 갈색
BRN: 109603 · 109603
InChI: 1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6)
InChIKey: GUABFMPMKJGSBQ-UHFFFAOYSA-N
SMILES: Cc1cnc(N)s1
LogP: 1.61 at · 1.61 at 38℃
표면장력: 72.6 mN/m · 72.6mN/m at 1.02g/L and 20℃
NIST: 2 · Thiazole, 2-amino-5-methyl-(7305-71-7)

화학적 성질

white to light yellow crystal powde

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P260, P264, P270, P273, P301+P317, P319, P330, P391, and P501 (click each P-code to see the statement)

Warning

H302 (96.4%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P264, P270, P273, P301+P317, P319, P330, P391, and P501 (click each P-code to see the statement)

유해성 정보

Regulatory InformationStatus: Active Update: 17-10-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/25186

Hazard Classes and Categories · 4건

Acute Tox. 4 (96.4%)

Acute Tox. 4 (100%)

Acute toxicity - category 4

Acute Tox. 4 *

안전 데이터

wgk: 3
ridadr: 2811
HS 번호: 29341000
risk_code: 22-48/22-50/53-36/37/38
hazard_code: Xn,N,Xi
safety_code: 60-61-29-26-37/39
포장분류: III
위험 등급: 9
위험 참고 사항: Irritant/Keep Cold
Hazard Classifications: Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1STOT RE 2
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야 · 2건

용도An aminothiazole derivative used in characterization and DNA-interaction studies via formation of metal complexes that bind competitively to DNA. 2-Amino-5-methylthiazole can be used in solar cells to influence the interaction with the TiO2 photoelectrode, which in turn alters the dye-sensitized solar cell performance.

일반 설명2-Amino-5-methylthiazole is a heterocyclic building block. It is one of the major alkaline metabolite of tenoxicam (TX) and meloxicam (MX).

상·하류 제품 정보

상류 원료

티오요소 1,2-Propadiene, 1-isothiocyanato-Meloxicam 2-브로모프리오피오날데하이드디에틸아세탈 2-브로모-프로피온알데히드 클로로프로판알 2-Methyl-4-hydroxy-2H-1,2-benzisothiazine-3-carboxylic acid ethyl ester-1,1-diox 클로로아세톤 프로피온알데히드 싸이오사이안산 칼륨 살리실 알데히드

하류 제품

2-클로로-5-메틸티아졸 5-메틸티아졸 티아졸,2-플루오로-5-메틸-5-methyl-4-(trifluoromethyl)thiazol-2-amine Ethyl 2-Methyl-5-oxo-[1,3]thiazolo[3,2-a]pyridine-6-carboxylate Formamide, N-(5-methyl-2-thiazolyl)-

공급사100 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

화합물 노트

불러오는 중…

2-Amino-5-methylthiazole

기본 정보

개요