4-(2-아미노프로필)페놀

Hydroxyamfetamine

HCID 3651CAS 103-86-6
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기본 정보

표준 SMILES
CC(N)Cc1ccc(O)cc1
InChIKey
GIKNHHRFLCDOEU-UHFFFAOYSA-N
분자식
C9H13NO
평균 분자량
151.21 g/mol
단동위원소 질량
151.09971404

개요

4-(2-aminopropyl)phenol is a member of amphetamines.

이름 및 식별자

우선 이름
Hydroxyamfetamine
IUPAC
4-(2-aminopropyl)phenol
현지명
4-(2-아미노프로필)페놀
영어명
4-(2-aminopropyl)phenol
분자식
C9H13NO
분자량
151.21

이름 및 동의어

4-(2-Aminopropyl)phenolhydroxyamphetamine103-86-6HydroxyamfetamineNorveritolPulsotonOxamphetaminiumOksamfetaminOxamfetaminParedrinexNov-Pholedrinp-(2-Aminopropyl)phenol
이름 더 보기
4-(2-아미노프로필)페놀p-하이드록시암페타민p-하이드록시암페타민4-(2-아미노프로필)페놀Norpholedrinep-Hydroxyamphetamine.alpha.-MethyltyraminePhenol,4-(2-aminopropyl)-Dl-p-(2-aminopropyl)phenol4-Hydroxy-.alpha.-methylphenethylamine2-(4-Hydroxyphenyl)-1-methylethylamine
Phenol, p-(2-aminopropyl)-DL-p-Hydroxyamphetamine1-p-Hydroxyphenyl-2-propylaminedl-4-hydroxyamphetamine2-Amino-1-(p-hydroxyphenyl)propaneNSC 170995Hydroxyamfetamine [INN]Hidroxianfetamina

데이터베이스 식별자

CAS
103-86-6
PubChem CID
3651
DTXSID
DTXSID3023134
ChEMBL
CHEMBL1546
ChEBI
CHEBI:103855
UNII
FQR280JW2N
EC Number
203-152-8
Nikkaji
J182.169E

물성

구조 계산 물성

XLogP
1.4
극성 표면적
46.3 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
2
회전 가능 결합 수
2
무거운 원자 수
11

실험 및 물리화학적 성질

DrugsDEA NFLIS-Drug Category -> Phenethylamines (Amphetamines) (S)

물리화학적 성질

녹는점
125 · 125-126 °C
끓는 점
279.2 · 279.2±15.0 °C(Predicted)
밀도
1.07 · 1.070±0.06 g/cm3(Predicted)
저장 조건
-20 °C · Store at -20°C
물리적 상태
Solid
산도 계수 (pKa)
9.83 · 9.83±0.15(Predicted)

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

유해성 정보

Hazard Classes and CategoriesAcute Tox. 4 (100%)

안전 데이터

독성
LDLo intravenous in rat: 100mg/kg

화학 및 산업

약리 정보

Protein BindingIntended for local use only (ophthalmic use).
Mechanism of ActionHydroxyamphetamine hydrobromide is an indirect acting sympathomimetic agent which causes the release of norepinephrine from adrenergic nerve terminals, resulting in mydriasis.
Metabolism/Metabolites · 2건

Intended for local use only (ophthalmic use).

4-Hydroxyamphetamine is a known human metabolite of Amphetamine.

FDA Pharmacological Classification · 5건

FQR280JW2N

HYDROXYAMPHETAMINE

Mechanisms of Action [MoA] - Adrenergic Agonists

Established Pharmacologic Class [EPC] - Adrenergic Receptor Agonist

Hydroxyamphetamine is an Adrenergic Receptor Agonist. The mechanism of action of hydroxyamphetamine is as an Adrenergic Agonist.

Absorption, Distribution and Excretion · 4건

Intended for local use only (ophthalmic use).

Intended for local use only (ophthalmic use).

Intended for local use only (ophthalmic use).

Intended for local use only (ophthalmic use).

Tissue LocationsKidney

상·하류 제품 정보

공급사7 곳

浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
青岛海智微元生物科技有限公司18317699790 18317699790 · [email protected]
上海珞珐生化科技有限公司021-51111890 15317326293 · [email protected]
广州佳途科技股份有限公司020-81960175-877 18933936954 · [email protected]

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