기본 정보
- CAS
21442-01-3- 표준 SMILES
C=C(C)C(=O)NCC(C)O- InChIKey
OKPYIWASQZGASP-UHFFFAOYSA-N- 분자식
- C7H13NO2
- 평균 분자량
- 143.18 g/mol
- 단동위원소 질량
- 143.09462866
개요
See also: Mureletecan (monomer of).
이름 및 식별자
- 우선 이름
- N-(2-hydroxypropyl)methacrylamide
- IUPAC
- N-(2-hydroxypropyl)-2-methylprop-2-enamide
- 현지명
- N-(2-하이드록시프로필)메타크릴아미드
- 영어명
- N-(2-Hydroxypropyl)methacrylamide
- 분자식
- C7H13NO2
- 분자량
- 143.18
이름 및 동의어
N-(2-Hydroxypropyl)methacrylamide21442-01-3HPMA polymerR3F262Z4E0poly(hydroxypropyl methacrylamide)RefChem:7879801-057-12-hydroxypropyl methacrylamideN-(2-hydroxypropyl)-2-methylprop-2-enamide2-Propenamide,N-(2-hydroxypropyl)-2-methyl-MFCD00080531N-(2-HYDROXYPROPYL) METHACRYLAMIDE
이름 더 보기
N-(2-하이드록시프로필)메타크릴아미드DK667DK668DKFELEX0166N-(2-HYDROXYPROPYL)METHACRYLAMIDN-(2-Hydroxypropyl)methacrylamide,98%N - (2-hydroxypropyl) methylacrylamide2-Hydroxypropyl methacrylamide 99% (GC)N-(2-Hydroxypropyl)-2-methyl-prop-2-enamide
2-Propenamide, N-(2-hydroxypropyl)-2-methyl-ACRYLAMIDE, N-(2-HYDROXYPROPYL)-2-METHYL-AKOS006344692HY-W077028SS-48551-(METHACRYLOYLAMINO)PROPAN-2-OLSY2380962-Propenamide, N-(2-hydroxypropyl)-2-me
데이터베이스 식별자
- CAS
21442-01-3、40704-75-4
물성
구조 계산 물성
- XLogP
- 0.3
- 극성 표면적
- 49.3 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 10
- 형식 전하
- 0
- 복잡도
- 143
물리화학적 성질
- 녹는점
- 67.92 °C · 67.92°C
- 끓는 점
- 321.2 · 321.2±34.0 °C(Predicted)
- 밀도
- 1.002 g/mL · 1.002 g/mL ((predicted))
- 저장 조건
- 2 · 2-8°C
- 용해도
- DMSO에 용해됨
- 산도 계수 (pKa)
- 14.43 · 14.43±0.20(Predicted)
- 물리적 상태
- 가루
- 색상
- White to off-white
- InChI
- 1S/C7H13NO2/c1-5(2)7(10)8-4-6(3)9/h6,9H,1,4H2,2-3H3,(H,8,10)
- InChIKey
- OKPYIWASQZGASP-UHFFFAOYSA-N
- SMILES
- CC(O)CNC(=O)C(C)=C
안전 및 규제
GHS 분류
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
안전 데이터
- wgk
- 3
- HS 번호
- 2924297099
- risk_code
- 36/37/38
- safety_code
- 26-36/37/39
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
개요N-(2-hydroxypropyl)methacrylamide (HPMA) is an important hydrophilic monomer. Due to the non-toxic, non-immunogenic properties and prolonged circulation time of both its homopolymers and copolymers, it is widely employed in the preparation of PHPMA copolymers (a polymer-drug conjugate) for use in the biopharmaceutical industry. For instance, poly(HPMA-co-MA-GFLG-doxorubicin) represents the first intravenous tumour-targeting polymeric prodrug to enter clinical trials. HPMA polymers and copolymers are also employed in the fabrication of biocompatible medical materials such as hydrogels[1].
용도Monomers to synthesize biocompetible polymers and copolymers for drug carriers, protein conjugates and hydrogels in biomedical applications.
공급사83 곳
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]
Junwee Chemical co., Ltd.+86-571-85808636 +86-13958122542 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
上海埃玛诺生物科技有限公司17302153218
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
郑州研德生物科技有限公司
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