기본 정보
- 표준 SMILES
COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC.Cl- InChIKey
IWSWDOUXSCRCKW-UHFFFAOYSA-N- 분자식
- C19H26ClN5O4
- 평균 분자량
- 423.9 g/mol
- 단동위원소 질량
- 423.16733199
개요
See also: Terazosin (has active moiety); Terazosin Hydrochloride (annotation moved to).
이름 및 식별자
- 우선 이름
- Terazosin Hydrochloride Anhydrous
- IUPAC
- [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone;hydrochloride
이름 및 동의어
63074-08-8Terazosin HClTerazosin hydrochloride anhydrousPiperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride8QOP8Z9955ABBOTT-45975 ANHYDROUSRefChem:932721613-138-7HytrinVasocard(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone hydrochlorideMLS000040261
이름 더 보기
Terazosin (hydrochloride)ZayaselMFCD004679656,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloridePiperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, monohydrochlorideSMR000044015Prazosin Tetrahydro Impurity1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride
데이터베이스 식별자
- CAS
63074-08-8、70024-40-7- PubChem CID
- 44383
- DTXSID
DTXSID7045493- ChEMBL
CHEMBL1256665- UNII
- 8QOP8Z9955
- EC Number
- 613-138-7
물성
구조 계산 물성
- 극성 표면적
- 103 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 8
- 회전 가능 결합 수
- 4
- 무거운 원자 수
- 29
- 형식 전하
- 0
- 복잡도
- 544
실험 및 물리화학적 성질
Collision Cross Section195.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 25% (1 of 4) of reports.
Warning
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
P203, P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P318, P330, P337+P317, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 4 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesAcute Tox. 4 (50%)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS.
Drugs used in the treatment of urological conditions and diseases such as URINARY INCONTINENCE and URINARY TRACT INFECTIONS.
용도 및 제조
UsesUse (kg; approx.) in Germany (2009): >75
관련 반응
5건
연결된 노트
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