아세틸메티오닌

N-acetyl-L-methionine

HCID 448580CAS 65-82-7

기본 정보

표준 SMILES
CSCC[C@H](NC(C)=O)C(=O)O
InChIKey
XUYPXLNMDZIRQH-LURJTMIESA-N
분자식
C7H13NO3S
평균 분자량
191.25 g/mol
단동위원소 질량
191.06161445

이름 및 식별자

우선 이름
N-acetyl-L-methionine
IUPAC
(2S)-2-acetamido-4-methylsulfanylbutanoic acid
현지명
아세틸메티오닌
영어명
N-Acetyl-L-methionine
분자식
C7H13NO3S
분자량
191.25

이름 및 동의어

N-Acetyl-L-methionine65-82-7N-AcetylmethionineAcetyl-L-methionineMethionamineThiomedonAcetylmethionineL-(N-Acetyl)methionineL-Methionine, N-acetyl-MethioninAcMetMethionine, N-acetyl-, L-
이름 더 보기
아세틸메티오닌NAMAC-MET-OHN-ACETYL-L-METHIONINE:AC-MET-OHn-acetyl-l-methionin01310-25GN-AC-L-MET
N-Ac-MetNalpha-acetyl-L-methionine(2S)-2-acetamido-4-methylsulfanylbutanoic acid(2S)-2-acetamido-4-(methylsulfanyl)butanoic acidFOLLICUSAN9J12WX5B6ACHEBI:21557DTXSID00883214

데이터베이스 식별자

CAS
65-82-7
PubChem CID
448580
DTXSID
DTXSID00883214
ChEBI
CHEBI:21557
UNII
9J12WX5B6A
EC Number
200-617-7
Nikkaji
J4.840B

물성

구조 계산 물성

XLogP
0.1
극성 표면적
91.7 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
4
회전 가능 결합 수
5
무거운 원자 수
12

실험 및 물리화학적 성질

LogP-0.03
Solubility · 2건

307000

307mg/mL at 25 °C

Melting Point · 2건

105.5

105.5 °C

Physical DescriptionSolid
Collision Cross Section · 2건

150.1 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)];142.6 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

142.7 Ų [M-H]-;150.2 Ų [M+Na]+

물리화학적 성질

녹는점
103 · 103-106 °C(lit.)
끓는 점
235 °C · 235 °C(Press: 12 Torr)
밀도
1.2684 · 1.2684 (rough estimate)
굴절률
-21 ° · -21 ° (C=1, H2O)
저장 조건
Sealed in dry,Room Temperature
용해도
100 mg/mL, · 메탄올: 용해성100mg/mL, 투명, 무색

화학적 성질

white crystals

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 57.1% (4 of 7) of all reports.

Danger

H315 (28.6%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (14.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (28.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (28.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 4 of 7 reports by companies.;There are 3 notifications provided by 3 of 7 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 2건

Regulation (EC) No 178/2002 (amended)

L-Methionine, N-acetyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesSkin Irrit. 2 (28.6%);Eye Dam. 1 (14.3%);Eye Irrit. 2A (28.6%);STOT SE 3 (28.6%)

독성 정보

Toxicity Summary · 2건

The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Acetyl Methionine

Safe for use in cosmetics, with qualifications

규제 정보

Regulatory Information · 2건

Regulation (EC) No 178/2002 (amended)

L-Methionine, N-acetyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
PD0480000
HS 번호
29309070
risk_code
36/37/38
hazard_code
Xi

화학 및 산업

약리 정보

Tissue LocationsPlacenta

용도 및 제조

UsesCIR ingredient: Acetyl Methionine
Use ClassificationCosmetics -> Skin conditioning
General Manufacturing InformationL-Methionine, N-acetyl-: ACTIVE

공급사50 곳

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

추가 설명

정의ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.

관련 반응

15건

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