Oleylamine (HCID 5356789)

개요

promotes fusion of mouse A(9) fibroblasts; RN given refers to parent cpd with unspecified isomeric designation; structure

이름 및 식별자

우선 이름: Oleylamine
IUPAC: (Z)-octadec-9-en-1-amine
현지명: 올레일아민
영어명: Oleylamine
분자식: C18H37N
분자량: 267.49

이름 및 동의어

OleylamineOleamineOleyl amine112-90-3Armeen OOleinamineNoram OCIS-9-OCTADECENYLAMINEAlamine 11OleylaminKemamine P 9899-Octadecenylamine, (Z)-

이름 더 보기

올레일아민올레아민(z)-9-옥타데켄-1-아민(Z)-9-옥타데켄일아민9-옥타데켄일아민시스-1-아미노-9-옥타데켄시스-9-옥타데켄일아민올린아민40%9-OCTADECENYLAMINEeyLAO Vnoramoarmeenoalamine11

(Z)-Octadec-9-enylamineZDQ1JWQ8DTNSC-664611-octadeceneamine hydrofluorideoleoylamineRefChem:577369oleylamine phosphate (1:1), (Z)-204-015-5

데이터베이스 식별자

CAS: 112-90-3、1838-19-3
PubChem CID: 5356789
DTXSID: DTXSID8026933
ChEMBL: CHEMBL1976606
UNII: ZDQ1JWQ8DT
EC Number: 204-015-5
Nikkaji: J59.382F

물성

구조 계산 물성

XLogP: 7.6
극성 표면적: 26 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 1
회전 가능 결합 수: 15
무거운 원자 수: 19
형식 전하: 0
복잡도: 175

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic

CosmeticsAntistatic

Vapor Pressure0.0001 [mmHg]

Food Contact SubstancesFCS -> FDA Cumulative Estimated Daily Intake (CEDI)

Physical Description · 2건

Liquid; CBI

Liquid; mp = 10-20 deg C; [IUCLID] Light yellow pasty liquid with an amine-like odor (mp = 15-30 deg C); [ECHA] Slightly beige paste; [MSDSonline]

Collision Cross Section180.2 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID8026933]

물리화학적 성질

녹는점: 18 · 18-26 °C (lit.)
끓는 점: 348 · 348-350 °C (lit.)
밀도: 0.813 g/mL · 0.813 g/mL at 25 °C (lit.)
증기압: 8 mm · 8 mm Hg ( 135 °C)
굴절률: 20 · n20/D 1.4596(lit.)
인화점: 310 °F · 310 °F
저장 조건: Keep in dark place,Inert atmosphere,Room temperature
물리적 상태: 액체
산도 계수 (pKa): 10.67 · 10.67±0.10(Predicted)
색상: 무색의
냄새: 약간 아민/레몬 냄새
수용성: 불용성
BRN: 1723960 · 1723960
안정성: 안정적인. 산, 산 염화물, 산 무수물, 산화제와 호환되지 않습니다.
화장품 원료 기능: 대전방지제
InChI: 1S/C18H37N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19/h9-10H,2-8,11-19H2,1H3/b10-9-
InChIKey: QGLWBTPVKHMVHM-MDZDMXLPSA-N
SMILES: [H]\C(CCCCCCCC)=C(/[H])CCCCCCCCN
LogP: 7.78 · 7.780 (est)
EPA: Oleylamine (112-90-3)

화학적 성질

beige paste or powder

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P270, P271, P273, P280, P301+P316, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P321, P330, P331, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for 3.7% (60 of 1620) of reports.

Danger

H302 (90.6%): Harmful if swallowed [Warning Acute toxicity, oral]

유해성 정보

Regulatory Information · 3건

Chemical: 9-Octadecen-1-amine, (Z)-

9-Octadecen-1-amine, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecen-1-amine, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Oleyl amine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Primary aliphatic (C12-22) and fatty amines: Human health tier II assessment

Hazards Summary · 1건

Concentrations of 1.5% and 3% in corn oil produced moderate to severe skin irritation in rats; Post-implantation mortality observed in mice following single oral dose on ninth day of pregnancy; No evidence of teratogenicity in rats or rabbits at gavage doses maternally toxic; No evidence of mutagenicity; [IUCLID] Corrosive to rabbit skin; Effects in 28-day gavage study with rats include abnormal gait, decrease in weight gain, and minor toxicity to the liver and kidneys; No histopathological effects observed in reproductive organs; No evidence of mutagenicity, teratogenicity, or developmental toxicity; [ECHA] Causes burns; Harmful by ingestion, inhalation, and skin absorption; Inhalation can cause corrosive effects on the upper respiratory tract and lungs; [Aldrich MSDS]

DOT Hazard Classification · 2건

Oleylamine

Marine pollutant

Hazard Classes and Categories · 4건

Acute Tox. 4 (90.6%)

Acute toxicity - category 4

Acute toxicity (Oral) - Category 4

Acute Tox. 4

독성 정보

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.

TSCA Test Submissions · 1건

The mutagenicity of (Z)-9-octadecenylamine (ODA) was evaluated in Salmonella tester strains TA98, TA100, TA1535, TA1537 and TA1538, both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Based on preliminary bacterial toxicity determinations, ODA, diluted with acetone, was tested for mutagenicity at concentrations up to 20 ug/plate for nonactivated cultures and concentrations up to 200 ug/plate for activated cultures using the plate incorporation method. ODA did not cause a positive response in any of the bacterial tester strains, either with or without metabolic activation.

안전 데이터

wgk: 2
tsca: TSCA listed
rtecs: RG4130000
ridadr: UN 2735 8/PG 2
독성: LD50 intraperitoneal in mouse: 888mg/kg
HS 번호: 29215900
risk_code: 34-22-50/53
hazard_code: C,N
safety_code: 26-36/37/39-45-24/25
포장분류: III
위험 등급: 8
기존화학 물질: KE-26433
Hazard Classifications: Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1Asp. Tox. 1Eye Dam. 1Skin Corr. 1BSTOT RE 2STOT SE 3
스토리지 클래스: 8A - Combustible corrosive hazardous materials
유해 물질 데이터: 112-90-3(Hazardous Substances Data)

화학 및 산업

용도 및 제조

Uses · 6건

Used as an intermediate, surfactant in textile production, and cosmetic ingredient; Amine and organic salts: Used as petroleum product and lubricant additives, corrosion inhibitors (i.e. in oil fields), ore flotation reagents, wetting agents for asphalt, and emulsifiers; [HSDB] Used in the EU as intermediate, flotation agent for metals, lubricant in metal processing, fuel additive, corrosion inhibitor, and antistatic agent for paints; [ECHA]

Petroleum Production and Refining [Category: Industry]

...SERIES OF PRIMARY, SECONDARY, & ALIPHATIC AMINES, ORG SUBSTITUTED AMMONIA DERIV.../USED AS/ CORROSION INHIBITORS, ORE FLOTATION AGENTS, TEXTILE FINISHING AGENTS, ASPHALT ANTISTRIPPING AGENTS, RUBBER COMPOUNDING, COLOR PARTICLE DISPERSION, PETROLEUM PRODUCT ADDITIVES, CHEMICAL INTERMEDIATES /ALAMINE/

...SERIES OF STRAIGHT CHAIN AMINES...FROM C12 THROUGH C22... /WHICH/ ARE STRONGLY HYDROPHOBIC & ARE BIODEGRADABLE. .../USED AS/ CATIONIC INTERMEDIATES; REMOVAL OF MOISTURE FROM SURFACES /KEMAMINES/

CHEM INT FOR QUATERNARY AMMONIUM SALTS

CHEM INT FOR OLEYL DIAMINE & ETHOXYLATED OLEYLAMINE

U.S. Exports · 2건

(1979) No Data

(1981) No Data

U.S. Imports · 2건

(1979) No Data

(1981) No Data

U.S. Production · 3건

2023: 8,500,000 - <10,000,000 lb

(1979) 2.24X10+9 GRAMS

(1981) 2.49X10+9 GRAMS

Consumer UsesOther

Industry UsesIntermediate

응용 분야 · 2건

용도Oleylamine is a long-chain primary alkylamine broadly used in the synthesis of metallic nanostructures. A variety of metallic nanostructures including Au, Ag, Pt, Pd, and their alloy has been synthesized in the presence of oleylamine. It has several important functions in the synthesis of metallic nanostructure. Oleylamine can simultaneously function as a solvent for the reaction mixture and stabilizing agent for metallic nanostructures. In addition, oleylamine has a boiling point of 364 °C; therefore, it can be used to synthesize metallic nanostructures at high temperatures.

일반 설명Oleylamine (OAm) is a long chain primary alkyamine, that acts as an electron donor at elevated temperatures. OAm exhibits affinity to metals through NH2 functional groups. FTIR spectra of OAm has been reported. Oleylamine acts as strong reducing agent as well as a stabilizer in the synthesis of nanoparticle.