6-Maleimidohexanoic acid (HCID 573683)

이름 및 식별자

우선 이름: 6-Maleimidohexanoic acid
IUPAC: 6-(2,5-dioxopyrrol-1-yl)hexanoic acid
현지명: 3-말레이미도-프록실
영어명: 6-Maleimidocaproic acid
분자식: C10H13NO4
분자량: 211.21

이름 및 동의어

6-Maleimidocaproic acid6-Maleimidohexanoic acidRefChem:543501611-311-155750-53-36-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid6-Maleimidocapronic acid1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-6-(2,5-dioxopyrrol-1-yl)hexanoic acidMFCD00043140Maleimide-(CH2)5-COOHN-(5-Carboxypentyl)maleimide

이름 더 보기

3-말레이미도-프록실6-말레이미도헥산노익산6-말레이미도카프로산EMCA6-(2,5-Dioxo-2H-pyrrol-1(5H)-yl)hexanoic acidMalHex6-MaleimidocaproicAciMal-(CH2)5-COOH (EMCA)

N-Maleoyl-6-aminocaproic acidSCHEMBL43969CHEMBL47391CS-M1809N-(6-oxo-6-hydroxyhexyl)maleimideBP-20415PD127389SY030571

데이터베이스 식별자

CAS: 55750-53-3
PubChem CID: 573683
DTXSID: DTXSID10876051
ChEMBL: CHEMBL47391
ChEBI: CHEBI:176414
EC Number: 611-311-1
Nikkaji: J685.630F

물성

구조 계산 물성

XLogP: 1.1
극성 표면적: 74.7 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 4
회전 가능 결합 수: 6
무거운 원자 수: 15
형식 전하: 0
복잡도: 291

물리화학적 성질

녹는점: 86 · 86-91 °C
끓는 점: 407.3 · 407.3±28.0 °C(Predicted)
밀도: 1.285 · 1.285±0.06 g/cm3(Predicted)
저장 조건: 2 · 2-8°C
용해도: DMSO(약간 용해됨), 에틸아세테이트(약간 용해됨)
물리적 상태: 가루
산도 계수 (pKa): 4.74 · 4.74±0.10(Predicted)
색상: 흰색에서 연한 노란색
수용성: 물, 메탄올, 에탄올, 디메틸설폭사이드에 용해됩니다. 에테르에 불용성.
BRN: 1532405 · 1532405
InChI: InChI=1S/C10H13NO4/c12-8-5-6-9(13)11(8)7-3-1-2-4-10(14)15/h5-6H,1-4,7H2,(H,14,15)
InChIKey: WOJKKJKETHYEAC-UHFFFAOYSA-N
SMILES: N1(CCCCCC(O)=O)C(=O)C=CC1=O
EPA: 1 H-Pyrrole-1-hexanoic · 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo- (55750-53-3)

화학적 성질

White to yellow solid, powder, crystals or crystaline powder.

안전 및 규제

GHS 분류

GHS Classification · 5건

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H318 (73.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (25%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (98.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 56 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Dam. 1 (73.2%)；Eye Irrit. 2 (25%)；STOT SE 3 (98.2%)

안전 데이터

wgk: 3
HS 번호: 29251900
risk_code: 36/37/38-41-37/38
hazard_code: Xi
safety_code: 26-36-39
F 고인화성물질: 10-21
Hazard Classifications: Skin Irrit. 2STOT SE 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

상·하류 제품 정보

상류 원료

하류 제품

MC-Val-Cit-PAB Mc-Val-Cit-PABC-PNP 맥MMAE CarbaMicacid,[5-(2,5-디히드로-2,5-디옥소-1H-피롤-1-일)펜틸]-,1,1-디메틸에틸에스테르 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2-[(1,1-diMethylethoxy)carbonyl]hydrazide

공급사50 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海杰又杰新材料科技有限公司021-64837106 13564410395

T&W GROUP021-61551611 13296011611 · [email protected]

韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]

추가 설명 · 1건

정의ChEBI: 6-Maleimidocaproic acid is a medium-chain fatty acid. It contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.