Dibenamine hydrochloride (HCID 5925)

이름 및 식별자

우선 이름: Dibenamine hydrochloride
IUPAC: N,N-dibenzyl-2-chloroethanamine;hydrochloride
영어명: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
분자식: C16H19Cl2N
분자량: 296.23

이름 및 동의어

55-43-6Dibenamine hydrochlorideN-(2-Chloroethyl)dibenzylamine hydrochlorideDibenzylchlorethamine hydrochlorideN,N-Dibenzyl-2-chloroethylamine hydrochlorideDibenamine HClN,N-Dibenzylaminoethyl chloride hydrochlorideDibenzylchlorethylamine hydrochloride2-Chloroethyldibenzylamine hydrochlorideDibenzyl(2-chloroethyl)ammonium chloride2-Dibenzylaminoethyl chloride hydrochlorideEINECS 200-234-5

이름 더 보기

Sympatholytin hydrochlorideN-(2-CHLOROETHYL)DIBENZYLAMINE HCLn,n-dibenzyl-2-chloroethylamineHCldibenzylchlorethylaminehydrochlorideDibenamine hydrochloride, 10 mM in DMSOn-(2-chloroethyl)-dibenzylaminhydrochlorideN,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE

NSC 11491beta-Chloroethyldibenzylamine hydrochlorideBenzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)-, hydrochlorideDIBENZYLAMINE, N-(2-CHLOROETHYL)-, HYDROCHLORIDEN,N-Dibenzyl-beta-chloroethylamine hydrochlorideNSC-11491W65S0F7870(2-Chloroethyl)dibenzylamine hydrochloride

데이터베이스 식별자

CAS: 55-43-6
PubChem CID: 5925
DTXSID: DTXSID3075337
ChEMBL: CHEMBL3272451
UNII: W65S0F7870
EC Number: 200-234-5

물성

구조 계산 물성

극성 표면적: 3.2 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 1
회전 가능 결합 수: 6
무거운 원자 수: 19
형식 전하: 0
복잡도: 187

물리화학적 성질

녹는점: 190 · 190-193 °C(lit.)
끓는 점: 449.72 °C · 449.72°C (rough estimate)
밀도: 1.1507 · 1.1507 (rough estimate)
굴절률: 1.63 · 1.6300 (estimate)
저장 조건: Inert atmosphere,Room Temperature
용해도: almost transparency in Methanol
물리적 상태: 결정성 분말
색상: 흰색에서 황백색까지
Merck: 14 · 14,2138
InChI: 1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H
InChIKey: LZXCEBPGNFLHEQ-UHFFFAOYSA-N
SMILES: Cl.ClCCN(Cc1ccccc1)Cc2ccccc2
EPA: N-(2-Chloroethyl)dibenzylamine hydrochloride (55-43-6)

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (97.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (97.5%)

안전 데이터

wgk: 3
rtecs: HQ6825000
독성: LD50 s.c. in mice: 800 mg/kg (Nickerson, Nomaguchi)
HS 번호: 29214900
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-37/39
위험 등급: IRRITANT
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야 · 2건

용도Sympatholytin was used as 5-Hydroxytryptamine antagonists in this study.Sympatholytin preferentially blocked postsynaptic alpha receptors.

일반 설명N-(2-Chloroethyl)dibenzylamine hydrochloride is also referred as dibenamine. Mechanism of protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with [N-(2-chloroethyl) dibenzylamine] hydrochloride has been investigated. It is a powerful adrenergic blocking agent, is known to modify the pharmacological effects of epinephrine.