Ciprofloxacin Hydrochloride Anhydrous
기본 정보
- CAS
86483-48-9- 표준 SMILES
Cl.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O- InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N- 분자식
- C17H19ClFN3O3
- 평균 분자량
- 367.8 g/mol
- 단동위원소 질량
- 367.1098973
개요
Ciprofloxacin hydrochloride (anhydrous) is the anhydrous form of the monohydrochloride salt of ciprofloxacin. It has a role as an antiinfective agent, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor and a topoisomerase IV inhibitor. It contains a ciprofloxacin.
이름 및 식별자
- 우선 이름
- Ciprofloxacin Hydrochloride Anhydrous
- IUPAC
- 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride
- 영어명
- Ciprofloxacin hydrochloride
- 분자식
- C17H18FN3O3.xHCl
- 분자량
- 367.81
이름 및 동의어
93107-08-5Ciprofloxacin Hydrochloride Anhydrous0MP32MFP6CRefChem:91867286483-48-91-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid xhydrochlorideCiprofloxacin monohydrochloride1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochlorideCHEBI:310388Bay o 9867Ciprofloxacin (monohydrochloride)
이름 더 보기
CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATECiprofloxacin base/HCLCifloxCiprofloxacin Impurity 14CIPROFLOXACIN HCL HYDRATECIPROFLOXACIN HCL (ANHYDROUS)Enrofloxacin nicotinate USP/EP/BP
BAY-O-9867CiproxanCiproxinciprofloxacin hydrochloride (anhydrous)BAY-o 98671-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochlorideciprofloxacine hydrochloride
물성
구조 계산 물성
- 극성 표면적
- 72.9 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 25
- 형식 전하
- 0
- 복잡도
- 571
물리화학적 성질
- 녹는점
- 300 °C · >300 °C
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- 물리적 상태
- 고체
- 색상
- 흰색에서 황백색까지
- BCS Class
- 3 · 3/1
- InChI
- InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
- InChIKey
- DIOIOSKKIYDRIQ-UHFFFAOYSA-N
- SMILES
- O=C1C(=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C12)C(=O)O.Cl
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Danger
H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesSkin Irrit. 2 (33.3%)
안전 데이터
- HS 번호
- 29419000
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Substances that inhibit the growth or reproduction of BACTERIA.
Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP1A2.
상·하류 제품 정보
상류 원료
추가 설명
ChEBI: The anhydrous form of the monohydrochloride salt of ciprofloxacin.
관련 반응
5건
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