염화크롬

Chromium(3+) trichloride

HCID 6452300

기본 정보

CAS: 10025-73-7
표준 SMILES: [Cl-].[Cl-].[Cl-].[Cr+3]
InChIKey: QSWDMMVNRMROPK-UHFFFAOYSA-K
분자식: Cl3Cr
평균 분자량: 158.35 g/mol

개요

Chromium(3+) trichloride is a chromium chloride with the chromium cation in the +3 oxidation state. It has a role as a sensitiser and a Lewis acid.

이름 및 식별자

우선 이름: Chromium(3+) trichloride
IUPAC: chromium(3+) trichloride
현지명: 염화크롬
영어명: chromium chloride
분자식: ClCr-
분자량: 158.36

이름 및 동의어

chromium(3+) trichloride39345-92-1Cl3CrChromium(iii)chloridetris(chloranyl)chromiumChromium(III); chlorideSCHEMBL49822CHROMIC CHLORIDE [MI]CHEBI:53351CHROMIC CHLORIDE [WHO-DD]AKOS024437430DB09129

이름 더 보기

염화크롬CHROMIUM CHLORIDE

CHROMIC CHLORIDE ANHYDROUS [HSDB]Chromium(III) chloride pound CrCl3 pound(c)F099239F987909

데이터베이스 식별자

CAS: 10025-73-7、39345-92-1、50925-66-1
PubChem CID: 6452300
ChEBI: CHEBI:53351
UNII: Z310X5O5RP
Nikkaji: J43.774C

물성

구조 계산 물성

극성 표면적: 0 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 3
회전 가능 결합 수: 0
무거운 원자 수: 4
형식 전하: 0
복잡도: 0

화학 및 산업

약리 정보

Protein BindingChromic chloride-induced binding of protein to red cells.

Pharmacodynamics · 1건

Trivalent chromium is part of glucose tolerance factor, an essential activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function. Providing chromium during TPN helps prevent deficiency symptoms including impaired glucose tolerance, ataxia, peripheral neuropathy and a confusional state similar to mild/moderate hepatic encephalopathy.

Mechanism of Action · 1건

Metallic chromium has no biological activity. Chromium is referred as a glucose tolerance factor. This glucose tolerance factor is a complex of molecules. Glycine, cysteine, glutamic acid and nicotinic acid along with chromium form this complex.

Biological Half-Life31- 41 hours

Metabolism/Metabolites · 1건

The metabolism of chromic chloride hexahydrate in guinea pigs for 60 days after intratracheal injection of 200 ug Cr 10 min after injection, 69% of the dose remained in the lungs, & only 4% was found in the blood & liver, kidneys, spleen. By 24 hr, 45% was still in the lungs, 6% was excreted in the urine, & only a very small % was found in the other tissues. The spleen was the only tissue that showed accumulation & that occurred during the 1st 48 hr.

Absorption, Distribution and Excretion · 3건

Chromium absorption can increase with exercise.

Most absorbed chromium is excreted rapidly in the urine, whereas unabsorbed chromium is excreted through feces.

Chromium is stored in liver, spleen, soft tissue and bone.