트리페닐메탄올
트라이페닐메틴올 · 트리페닐메탄올 · TRT-OH · TRIPHENYLCARBINOL · TRITYL ALCOHOL · Triphenylmethanol, (Triphenyl carbinol · Methanol, triphenyl- · Tritanol
식별자 및 물리적 특성
| CAS No. | 76-84-6 |
|---|---|
| 분자식 | C19H16O |
| 평균 분자량 | 260.3 g/mol |
| 단동위원소 질량 | 260.12011513 g/mol |
| SMILES | OC(c1ccccc1)(c1ccccc1)c1ccccc1 |
| InChIKey | LZTRCELOJRDYMQ-UHFFFAOYSA-N |
| PubChem CID | 6457 |
| ChEMBL | CHEMBL118166 |
| ChEBI | CHEBI:228440 |
| EC No. | 200-988-5 |
| DTXSID | DTXSID0058803 |
| 현지명 | 트리페닐메탄올 |
화학 및 물리적 성질
| XLogP | 3.7 |
|---|---|
| 극성 표면적 | 20.2 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 3 |
| 무거운 원자 수 | 20 |
| 형식 전하 | 0 |
| 복잡도 | 235 |
| Polymers | Other Classes -> Alcohols and Polyols, Other |
| SpringerMaterials Properties | 13C nuclear magnetic resonance spectrum |
| LogP(분배 계수) | 3.68 |
| 증기압 | 0.00000003 [mmHg] |
| Physical Description | Other Solid[Merck Index] White to cream crystalline powder[Alfa Aesar MSDS] |
| 녹는점 | 160-163 °C (lit.) |
| 끓는 점 | 360 °C (lit.) |
| 밀도 | d40 1.199 |
| 굴절률 | 1.6220 (estimate) |
| 인화점 | 360-380°C |
| 저장 조건 | 2-8°C |
| 용해도 | 디옥산: 0.1 g/mL, 투명 |
| pKa(산도 계수) | 12.73±0.29(Predicted) |
| 물리적 상태 | 미세 결정성 분말 |
| 색상 | 흰색에서 밝은 노란색 |
| 용해도 | 불용성 |
| Merck | 14,9739 |
| BRN | 1460837 |
| 안정성 | 안정적인. 타기 쉬운. 산화제, 산, 산 염화물, 산 무수물과 호환되지 않습니다. |
| InChI | 1S/C19H16O/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15,20H |
| InChIKey | LZTRCELOJRDYMQ-UHFFFAOYSA-N |
| SMILES | OC(c1ccccc1)(c2ccccc2)c3ccccc3 |
| NIST | Benzenemethanol, «alpha»,«alpha»-diphenyl-(76-84-6) |
| EPA | Benzenemethanol, .alpha.,.alpha.-diphenyl- (76-84-6) |
화학적 성질
Triphenylmethanol is a white powder or colorless, isolated crystals that are soluble in alcohol, ether, and benzene. It turns dark yellow when dissolved in concentrated sulfuric acid, colorless when dissolved in glacial acetic acid, and is insoluble in water and petroleum ether. It distills at 360-380°C without decomposition.
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 0.9% (1 of 114) of reports.WarningH315 (98.2%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 114 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Chemical: Benzenemethanol, .alpha.,.alpha.-diphenyl-Benzenemethanol, .alpha.,.alpha.-diphenyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Benzenemethanol, .alpha.,.alpha.-diphenyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 14-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/21505Benzenemethanol, .alpha.,.alpha.-diphenyl-: Does not have an individual approval but may be used under an appropriate group standard |
| 유해성 요약 | A skin and strong eye irritant[Alfa Aesar MSDS] See Chlorotriphenylmethane and Triphenylmethyl bromide. |
| Hazard Classes and Categories | Skin Irrit. 2 (98.2%) |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| 관세 코드 | 29062900 |
| 위험 문구(R) | 38-36/37/38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 22-24/25-36-26 |
| 기존화학 물질 | 2001-3-1908 |
| 저장 분류 | 11 - Combustible Solids |
용도
용도
Triphenylmethanol is used as a reagent in the research laboratory. It acts as an intermediate in the production of the commercially useful triarylmethane dyes. It is used in the preparation of triphenylmethane. It is also used as an antiproliferative agent. Further, it is used in the preparation of two-electron reduction product of pyrylogen. In addition to this, it reacts with triphenylphosphine oxide to form a 1:1 molecular complex. It serves as a specific clathrate host for methanol and dimethyl sulphoxide and forms clathrate inclusion complexes. Triphenylmethanol was used in the synthesis of of the two-electron reduction product of pyrylogen. It undergoes reduction to triphenylmethane by 9, 10-dihydro-10-methylacridine in the presence of perchloric acid.
일반 설명
Triphenylmethanol forms 1:1 molecular complex with triphenylphosphine oxide. It is a specific clathrate host for methanol and dimethyl sulphoxide and forms clathrate inclusion complexes. It undergoes reduction to triphenylmethane by 9, l0-dihydro-10-methylacridine in the presence of perchloric acid.
제조 및 합성 방법
제조 방법
Triphenylmethanol synthesis: Triphenylmethanol was prepared by the action of benzene with carbon tetrachloride in the presence of Aluminum chloride, followed by acidification and hydrolysis.Triphenylmethanol can also be prepared by the reaction of phenylmagnesium bromide with methyl benzoate (instead of benzophenone).Synthesis of Triphenylmethanol