Betamethasone Sodium Phosphate
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기본 정보
- CAS
151-73-5- 표준 SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)([O-])[O-].[Na+].[Na+]- InChIKey
PLCQGRYPOISRTQ-LWCNAHDDSA-L- 분자식
- C22H28FNa2O8P
- 평균 분자량
- 516.4 g/mol
- 단동위원소 질량
- 516.13012157
이름 및 식별자
- 우선 이름
- Betamethasone Sodium Phosphate
- IUPAC
- disodium;[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
- 영어명
- Betamethasone 21-phosphate disodium
- 분자식
- C22H28FNa2O8P
- 분자량
- 516.4
이름 및 동의어
151-73-5Betamethasone sodium phosphateBetamethasone disodium phosphateBetamethasone 21-disodium phosphateBetamethasone 21-phosphate disodiumBetamethasone 21-phosphate disodium saltBetamethazone disodium phosphateDTXSID80471377BK02SCL3W9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 21-(disodium phosphate)NSC-90616CHEBI:3078
이름 더 보기
DurabetasonbetnesolbentelanCelestanBentalanNSC 90616Vista-Methasone
DTXCID6027137Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11beta,16beta)-betamethason sodium phosphateVistamethasoneBetam-ophtalVistamethasone nNSC90616RefChem:54528
데이터베이스 식별자
- CAS
151-73-5
물성
구조 계산 물성보충 중
- 극성 표면적
- 147 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 9
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 34
- 형식 전하
- 0
- 복잡도
- 961
물리화학적 성질
- 녹는점
- 206 · 206-211°C
- 저장 조건
- room temp
- 용해도
- 물에 잘 녹고, 에탄올(96%)에 약간 녹으며, 염화메틸렌에는 거의 녹지 않습니다.
- 물리적 상태
- Solid
- 색상
- 흰색에서 황백색까지
- 수소이온지수(pH)
- 7.5 · 7.5~9.0(5g/l, 25℃)
- 수용성
- 50 mg/mL, · water: 50mg/mL, clear to very slightly hazy, faintly yellow
- Merck
- 14 · 14,1180
- 안정성
- 흡습성
- InChIKey
- PLCQGRYPOISRTQ-LWCNAHDDSA-L
- SMILES
- [C@@]12([H])C[C@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H].[Na+].[Na+] |&1:0,3,5,15,18,20,22,32,r|
- EPA
- .beta.-Methasone disodium phosphate (151-73-5)
화학적 성질
White or almost white powder, very hygroscopic.
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Danger
H302 (44.2%): Harmful if swallowed [Warning Acute toxicity, oral]；H330 (54.9%): Fatal if inhaled [Danger Acute toxicity, inhalation]；H360 (42.5%): May damage fertility or the unborn child [Danger Reproductive toxicity]；H360D (15%): May damage the unborn child [Danger Reproductive toxicity]；H372 (48.7%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]；H373 (12.4%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]；H410 (46.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
P203, P260, P264, P270, P271, P273, P280, P284, P301+P317, P304+P340, P316, P318, P319, P320, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 113 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
유해성 정보
Regulatory InformationBetamethasone sodium phosphate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety Information
IMAP assessments - Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-: Environment tier I assessment；IMAP assessments - Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-: Human health tier I assessment
Hazard Classes and Categories
화학 및 산업
약리 정보
MeSH Pharmacological Classification
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
용도 및 제조
Use ClassificationAnimal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
추가 설명
정의ChEBI: An organic sodium salt that is the disodium salt of betamethasone phosphate.
관련 반응
2건
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