1-페닐피페라진

1-Phenylpiperazine

HCID 7096CAS 4004-95-9

부분 구조 검색 유사 구조 찾기

기본 정보

표준 SMILES: c1ccc(N2CCNCC2)cc1
InChIKey: YZTJYBJCZXZGCT-UHFFFAOYSA-N
분자식: C10H14N2
평균 분자량: 162.23 g/mol
단동위원소 질량: 162.11569846

이름 및 식별자

우선 이름: 1-Phenylpiperazine
IUPAC: 1-phenylpiperazine
현지명: 1-페닐피페라진이염산염
영어명: 1-Phenylpiperazine dihydrochloride
분자식: C10H16Cl2N2
분자량: 235.15

이름 및 동의어

1-PHENYLPIPERAZINE92-54-6PhenylpiperazineDTXSID8057855J9225CBI7DDTXCID9031644RefChem:173105202-165-6N-PhenylpiperazinePiperazine, 1-phenyl-1-Phenyl-piperazineN-Phenyldiethylenediamine

이름 더 보기

1-페닐피페라진이염산염Nsc1508471-Phenylpiperazine2HCl1-Phenylpiperazine hHdrochloridePhenylpiperazine (hydrochloride)1-Phenylpiperazine dihydrochlorideN-Phenylpiperazine Dihydrochloride4-Phenylpiperazine Dihydrochloride1-PHENYLPIPERAZINE DIHYDROCHLORIDE 98%Piperazine, 1-phenyl-, dihydrochloride

4-phenylpiperazinen-phenyl piperazineMFCD00005957CHEMBL94341-Fenylpiperazin1-Fenylpiperazin [Czech]N-phenylpiperazinCCRIS 4334

데이터베이스 식별자

CAS: 4004-95-9、92-54-6
PubChem CID: 7096
DTXSID: DTXSID8057855
ChEMBL: CHEMBL9434
UNII: J9225CBI7D
EC Number: 202-165-6
Nikkaji: J35.451A

물성

구조 계산 물성

XLogP: 1.1
극성 표면적: 15.3 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 1
무거운 원자 수: 12
형식 전하: 0
복잡도: 124

실험 및 물리화학적 성질

Dissociation Constants9

물리화학적 성질

녹는점: 221 · 221-223°C
저장 조건: Hygroscopic, Refrigerator, Under Inert Atmosphere
용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)
물리적 상태: 고체
색상: 흰색에서 황백색까지
안정성: 흡습성

화학적 성질

White Solid

안전 및 규제

GHS 분류

GHS Classification · 5건

Danger

H301 (96.9%): Toxic if swallowed [Danger Acute toxicity, oral]；H310 (36.9%): Fatal in contact with skin [Danger Acute toxicity, dermal]；H311 (61.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H314 (98.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P262, P264, P270, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P361+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 65 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 3건

Status: Active Update: 09-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21606

Piperazine, 1-phenyl-, dihydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Phenylpiperazine: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesAcute Tox. 3 (96.9%)；Acute Tox. 2 (36.9%)；Acute Tox. 3 (61.5%)；Skin Corr. 1B (98.5%)

규제 정보

Regulatory Information · 3건

Status: Active Update: 09-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21606

Phenylpiperazine: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

신호 어: Warning
유해·위험 문구: 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H315

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.

A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).