Lactide
기본 정보
- CAS
33135-50-1- 표준 SMILES
CC1OC(=O)C(C)OC1=O- InChIKey
JJTUDXZGHPGLLC-UHFFFAOYSA-N- 분자식
- C6H8O4
- 평균 분자량
- 144.12 g/mol
- 단동위원소 질량
- 144.04225873
개요
Lactide is a member of dioxanes.
이름 및 식별자
- 우선 이름
- Lactide
- IUPAC
- 3,6-dimethyl-1,4-dioxane-2,5-dione
- 영어명
- poly(L-lactide)
- 분자식
- C6H8O4
- 분자량
- 144.12532
이름 및 동의어
95-96-5LACTIDEDilactidep-Dioxane-2,5-dione, 3,6-dimethyl-RefChem:57699202-468-33,6-Dimethyl-1,4-dioxane-2,5-dioneDL-LactideDL-Dilactide33135-50-11,4-Dioxane-2,5-dione, 3,6-dimethyl-3,6-Dimethyl-2,5-dioxo-1,4-dioxane
이름 더 보기
L-polylactidePoly(L-lactide) PLLARESOMER?L 210poly-l-lactidLACTEL BP-0600PURASORB(R) PLPURASORB(R) PL8PURASORB(R) PL6PURASORB(R) PL4PURASORB(R) PL2
Lactic acid, bimol. cyclic esterLACTIDE, DL-Propanoic acid, 2-hydroxy-, bimol. cyclic ester7EH08MWO6MMFCD00011685DTXSID7041253AI3-05059NSC-403080
데이터베이스 식별자
- CAS
33135-50-1、95-96-5- PubChem CID
- 7272
- DTXSID
DTXSID7041253- ChEMBL
CHEMBL3185272- ChEBI
CHEBI:177651- UNII
- 7EH08MWO6M
- EC Number
- 202-468-3、608-832-1
- Nikkaji
- J4.715E
물성
구조 계산 물성
- XLogP
- 0.6
- 극성 표면적
- 52.6 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 4
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 10
- 형식 전하
- 0
- 복잡도
- 155
실험 및 물리화학적 성질
Chemical ClassesOther Classes -> Other Organic Compounds
Physical Description
CBI
Solid; [Sigma-Aldrich MSDS]
물리화학적 성질
- 녹는점
- 153 °C · 153 °C
- 밀도
- 1.27 g/cm3 · 1.27 g/cm3
- 저장 조건
- 2 · 2-8°C
- 물리적 상태
- solid
- InChI
- InChI=1/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3/t3-,4-/s3
- InChIKey
- BHIWKHZACMWKOJ-UHFFFAOYSA-N
- SMILES
- O1[C@@H](C)C(=O)O[C@@H](C)C1=O |&1:1,6,r|
화학적 성질
White powder
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Aggregated GHS information provided per 158 reports by companies from 6 notifications to the ECHA C&L Inventory.
유해성 정보
Regulatory Information
1,4-Dioxane-2,5-dione, 3,6-dimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,4-Dioxane-2,5-dione, 3,6-dimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Dilactide (EC: 202-468-3)
Hazards SummaryCauses stomach ulceration and changes in renal tubules in 2-week intermittent oral studies of dogs; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See 4,4-Dimethyl-1,3-dioxane and 1,4-Dioxane.
Hazard Classes and CategoriesEye Irrit. 2A (100%)
안전 데이터
- wgk
- 3
- HS 번호
- 29181990
- safety_code
- 22-24/25
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
용도 및 제조
UsesUsed to make polylactic acid and cosmetics; [ExPub: ECHA REACH Registrations]
U.S. Production2023: 100,000,000 - <500,000,000 lb
Consumer UsesIntermediate
Industry UsesIntermediate
General Manufacturing Information
Plastics Product Manufacturing
1,4-Dioxane-2,5-dione, 3,6-dimethyl-: ACTIVE
응용 분야
용도Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.
일반 설명Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.
관련 반응
5건
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